Abstract
A total of 271 out of 757 patients who had suffered a myocardial infarction during 1966-7 were still alive after six years; these patients were subsequently followed up 15 years after the infarction. Two hundred and sixty eight (99%) of the patients alive at six years and 519 (95%) of the 549 originally discharged from hospital were traced. A coronary prognostic index, which had predicted survival both to three years and from three to six years after recovery from the infarct also predicted survival from six to 15 years after recovery. The major factor affecting survival to 15 years was age at the time of the original infarct. Among patients aged under 60 at the time of infarction women fared better than men (p = 0.027). Factors in the coronary prognostic index that were associated with impairment of left ventricular function at the time of infarction and that had predicted mortality to three years and from three to six years also predicted mortality from six to 15 years. These factors were cardiac enlargement, pulmonary venous congestion, and the presence of infarction before the index infarct. The dominant cause of death remained coronary heart disease and its complications.
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- BERKSON J., GAGE R. P. Calculation of survival rates for cancer. Proc Staff Meet Mayo Clin. 1950 May 24;25(11):270–286. [PubMed] [Google Scholar]
- Norris R. M., Bensley K. E., Caughey D. E., Scott P. J. Hospital mortality in acute myocardial infarction. Br Med J. 1968 Jul 20;3(5611):143–146. doi: 10.1136/bmj.3.5611.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Norris R. M., Brandt P. W., Caughey D. E., Lee A. J., Scott P. J. A new coronary prognostic index. Lancet. 1969 Feb 8;1(7589):274–278. doi: 10.1016/s0140-6736(69)91035-6. [DOI] [PubMed] [Google Scholar]
- Norris R. M., Caughey D. E., Deeming L. W., Mercer C. J., Scott P. J. Coronary prognostic index for predicting survival after recovery from acute myocardial infarction. Lancet. 1970 Sep 5;2(7671):485–487. doi: 10.1016/s0140-6736(70)90110-8. [DOI] [PubMed] [Google Scholar]
- Norris R. M., Caughey D. E., Mercer C. J., Scott P. J. Prognosis after myocardial infarction. Six-year follow-up. Br Heart J. 1974 Aug;36(8):786–790. doi: 10.1136/hrt.36.8.786. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peto R., Pike M. C., Armitage P., Breslow N. E., Cox D. R., Howard S. V., Mantel N., McPherson K., Peto J., Smith P. G. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples. Br J Cancer. 1977 Jan;35(1):1–39. doi: 10.1038/bjc.1977.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rude R. E., Muller J. E., Braunwald E. Efforts to limit the size of myocardial infarcts. Ann Intern Med. 1981 Dec;95(6):736–761. doi: 10.7326/0003-4819-95-6-736. [DOI] [PubMed] [Google Scholar]
- Taylor G. J., Humphries J. O., Mellits E. D., Pitt B., Schulze R. A., Griffith L. S., Achuff S. C. Predictors of clinical course, coronary anatomy and left ventricular function after recovery from acute myocardial infarction. Circulation. 1980 Nov;62(5):960–970. doi: 10.1161/01.cir.62.5.960. [DOI] [PubMed] [Google Scholar]