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. 1977 Aug;33(2):241–246.

Embryonic mouse thymocyte development. Enhancing effect of corticosterone at physiological levels.

M A Ritter
PMCID: PMC1445335  PMID: 305411

Abstract

The action of corticosterone on embryonic mouse thymus development has been studied in vitro. Effects of the hormone on lymphoid differentiation varied according to the dose. 0.2-1.0 microgram/ml had an enhancing effect, resulting in an increase in the proportion of Thy-1.2 positive cells as compared with control cultures. Two to fifty micrograms per millilitre had an inhibitory effect, appearing to selectively kill small lymphocytes while leaving large and medium lymphocytes intact. At higher does these immature cells were also killed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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