Abstract
The transfer of anaphylactic antibodies of classes IgE and IgGa from immunized female rats to babies was examined during primary and secondary immunization by injection, and also in rats infested with Trichinella spiralis. IgE antibodies were never detected in the blood of the babies, although they were sometimes detected in the milk in their stomachs. Similarly, no IgE antibodies were found in the serum of babies from mothers infested with Trichinella spiralis during pregnancy. IgGa antibodies were present in the serum and milk of the mothers following secondary immunization, and were readily absorbed through the intestine of the babies.
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Selected References
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- BENACERRAF B., LEVINE B. B. Immunological specificity of delayed and immediate hypersensitivity reactions. J Exp Med. 1962 May 1;115:1023–1036. doi: 10.1084/jem.115.5.1023. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BENACERRAF B., OVARY Z., BLOCH K. J., FRANKLIN E. C. Properties of guinea pig 7S antibodies. I. Electrophoretic separation of two types of guinea pig 7S antibodies. J Exp Med. 1963 Jun 1;117:937–949. doi: 10.1084/jem.117.6.937. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BINAGHI R. A., BENACERRAF B. THE PRODUCTION OF ANAPHYLACTIC ANTIBODY IN THE RAT. J Immunol. 1964 Jun;92:920–926. [PubMed] [Google Scholar]
- Binaghi R. A., Sarandon de Merlo E. Characterization of rat IgA and its non-identity with the anaphylactic antibody. Int Arch Allergy Appl Immunol. 1966;30(6):589–596. doi: 10.1159/000229845. [DOI] [PubMed] [Google Scholar]
- Esteves M. B., Sant'anna O. A., Annes V. C., Binaghi R. A. Characterization and properties of an anaphylactic 7S antibody in sheep. J Immunol. 1974 Feb;112(2):722–727. [PubMed] [Google Scholar]
- MOTA I. Biological characterization of "mast cell sensitizing" antibodies. Life Sci. 1963 Jul;(7):465–474. doi: 10.1016/0024-3205(63)90134-6. [DOI] [PubMed] [Google Scholar]
- McGhee J. R., Michalek S. M., Ghanta V. K. Rat immunoglobulins in serum and secretions: purification of rat IgM, IgA and IgG and their quantitation in serum, colostrum, milk and saliva. Immunochemistry. 1975 Oct;12(10):817–823. doi: 10.1016/0019-2791(75)90146-9. [DOI] [PubMed] [Google Scholar]
- Morse H. C., 3rd, Bloch K. J., Austen K. F. Biologic properties of rat antibodies. II. Time-course of appearance of antibodies involved in antigen-induced release of slow reacting substance of anaphylaxis (SRS-A rat); association of this activity with rat IgGa. J Immunol. 1968 Oct;101(4):658–663. [PubMed] [Google Scholar]
- NUSSENZWEIG R. S., MERRYMAN C., BENACERRAF B. ELECTROPHORETIC SEPARATION AND PROPERTIES OF MOUSE ANTIHAPTEN ANTIBODIES INVOLVED IN PASSIVE CUTANEOUS ANAPHYLAXIS AND PASSIVE HEMOLYSIS. J Exp Med. 1964 Aug 1;120:315–328. doi: 10.1084/jem.120.2.315. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Perrudet-Badoux A., Binaghi R. A. Isolation of properties of a soluble antigen of Trichinella spiralis. Immunology. 1974 Jun;26(6):1217–1223. [PMC free article] [PubMed] [Google Scholar]
