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. 1975 Jul;29(1):185–195.

Dog immunoglobulins. I. immunochemical characterization of dog serum, parotid saliva, colostrum, milk and small bowel fluid.

R J Heddle, D Rowley
PMCID: PMC1445854  PMID: 806517

Abstract

The levels of immunoglobulins A, M and G were measured in dog serum, colostrum, milk, parotid saliva and small bowel fluid using the single radial immunodiffusion method. All the external secretions except early colostrum, by contrast with serum, were found to be rich in IgA with small quantities of IgM and IgG. Exocrine immunoglobulins were partially characterized by gel filtration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSEN S. B., GLENERT J., WALLEVIK K. GAMMA GLOBULIN TURNOVER AND INTESTINAL DEGRADATION OF GAMMA GLOBULIN IN THE DOG. J Clin Invest. 1963 Dec;42:1873–1881. doi: 10.1172/JCI104872. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Axén R., Porath J., Ernback S. Chemical coupling of peptides and proteins to polysaccharides by means of cyanogen halides. Nature. 1967 Jun 24;214(5095):1302–1304. doi: 10.1038/2141302a0. [DOI] [PubMed] [Google Scholar]
  3. Brown W. R., Newcomb R. W., Ishizaka K. Proteolytic degradation of exocrine and serum immunoglobulins. J Clin Invest. 1970 Jul;49(7):1374–1380. doi: 10.1172/JCI106354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Eddie D. S., Schulkind M. L., Robbins J. B. The isolation and biologic activities of purified secretory IgA and IgG anti-Salmonella typhimurium "O" antibodies from rabbit intestinal fluid and colostrum. J Immunol. 1971 Jan;106(1):181–190. [PubMed] [Google Scholar]
  5. Gillette D. D., Filkins M. Factors affecting antibody transfer in the newborn puppy. Am J Physiol. 1966 Feb;210(2):419–422. doi: 10.1152/ajplegacy.1966.210.2.419. [DOI] [PubMed] [Google Scholar]
  6. Goudie R. B., Horne C. H., Wilkinson P. C. A simple method for producing antibody specific to a single selected diffusible antigen. Lancet. 1966 Dec 3;2(7475):1224–1226. doi: 10.1016/s0140-6736(66)92305-1. [DOI] [PubMed] [Google Scholar]
  7. Heddle R. J., Rowley D. Dog immunoglobulins. II. The antibacterial properties of dog IgA, IgM and IgG antibodies to Vibrio cholerae. Immunology. 1975 Jul;29(1):197–208. [PMC free article] [PubMed] [Google Scholar]
  8. Heremans J. F. Immunoglobulin formation and function in different tissues. Curr Top Microbiol Immunol. 1968;45:131–203. doi: 10.1007/978-3-642-50109-8_4. [DOI] [PubMed] [Google Scholar]
  9. Johnson J. S., Vaughan J. H. Canine immunoglobulins. I. Evidence for six immunoglobulin classes. J Immunol. 1967 May;98(5):923–934. [PubMed] [Google Scholar]
  10. Knop J., Breu H., Wernet P., Rowley D. The relative antibacterial efficiency of IgM, IgG and IgA from pig colostrum. Aust J Exp Biol Med Sci. 1971 Aug;49(4):405–413. doi: 10.1038/icb.1971.42. [DOI] [PubMed] [Google Scholar]
  11. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  12. Michael J. G., Ringenback R., Hottenstein S. The antimicrobial activity of human colostral antibody in the newborn. J Infect Dis. 1971 Nov;124(5):445–448. doi: 10.1093/infdis/124.5.445. [DOI] [PubMed] [Google Scholar]
  13. OUCHTERLONY O. Diffusion-in-gel methods for immunological analysis. Prog Allergy. 1958;5:1–78. [PubMed] [Google Scholar]
  14. Plaut A. G., Keonil P. Immunoglobulins in human small intestinal fluid. Gastroenterology. 1969 Mar;56(3):522–530. [PubMed] [Google Scholar]
  15. Ricks J., Roberts M., Patterson R. Canine secretory immunoglobulins: identification of secretory component. J Immunol. 1970 Dec;105(6):1327–1333. [PubMed] [Google Scholar]
  16. SCHEIDEGGER J. J. Une micro-méthode de l'immuno-electrophorèse. Int Arch Allergy Appl Immunol. 1955;7(2):103–110. [PubMed] [Google Scholar]
  17. Shearman D. J., Parkin D. M., McClelland D. B. The demonstration and function of antibodies in the gastrointestinal tract. Gut. 1972 Jun;13(6):483–499. doi: 10.1136/gut.13.6.483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Vaerman J. P., Heremans J. F. Distribution of various immunoglobulin containing cells in canine lymphoid tissue. Immunology. 1969 Oct;17(4):627–633. [PMC free article] [PubMed] [Google Scholar]
  19. Vaerman J. P., Heremans J. F. Origin and molecular size of immunoglobulin-A in the mesenteric lymph of the dog. Immunology. 1970 Jan;18(1):27–38. [PMC free article] [PubMed] [Google Scholar]
  20. Vaerman J. P., Heremans J. F. The immunoglobulins of the dog. II. The immunoglobulins of canine secretions. Immunochemistry. 1969 Nov;6(6):779–786. doi: 10.1016/0019-2791(69)90284-5. [DOI] [PubMed] [Google Scholar]

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