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. 2004 Sep;168(1):227–251. doi: 10.1534/genetics.104.026617

TABLE 6.

Genetic interactions withscribble—effect of halving the dosage of otherS(DmcycEJP) genes on the viability of hypomorphicscribble allele combinations

Total no. of progeny
Mutant allele x/+ or CyO/+;
scrib1or5/TM6B
x/+; scrib1/scrib5 % of expected no. of x/+ …scrib1/scrib5 progenya
2.1 (lgl) 27S3 304  0  0
E2S31 145  0  0
lgl4 248  0  0
2.2 (phyl) 28S2 231  0  0
2.3 65S12 227  0  0
36Fd 343  1  2
2.4 57S6 235  0  0
59S3 210  8 25
2.5 (dEB1) 42S11 147  3 13
2.9 E1S4 256  0  0
25S11 242  0  0
2.11 (scab) E(sev-cycE)e93  86  1  8
Total no. of progeny
Mutant allele x scribJ7b3or5 …/TM6B x scribJ7b3/scrib5 % of expected no. of x/+ …scrib1/scrib5 progenya
brm 2 401 47 24
mor 1 323 13  8
3.1 19S5 276 91 66
24SX 279 58 42
a

The expected number of scrib1/scrib5 progeny = total TM6B progeny/4 × 0.61 was derived as follows: The control cross of scrib1/TM6B × scrib5/TM6B gave 127 scrib1/scrib5 out of 627 total progeny, i.e., 61% of the expected number. To control for this, the percentage of the expected number of x/+ scrib1/scrib5 progeny has been adjusted by this factor. The weaker scrib allele combination, −/+ scribJ7b3/scrib5, gave expected Mendelian numbers of progeny. The expected number of scribJ7b3/scrib5 progeny = total number of TM6B progeny/2.