TABLE 2.
Gain-of-functioneas suppressors
| % bang sensitivity
|
|||||
|---|---|---|---|---|---|
| EP line | Test (n) | Control (n) | Map position |
Gene | Molecular function |
| EP(2)684 | 4 (229) | 100 (136) | 35D | escargot (esg) | Zn2+-finger transcription factor |
| EP(2)2009 | 11 (171) | 100 (253) | 35D | escargot (esg) | Zn2+-finger transcription factor |
| EP(2)633 | 20 (163) | 100 (194) | 35D | escargot (esg) | Zn2+-finger transcription factor |
| EP(2)2589 | 78 (147) | 100 (149) | 52B | Unknown | NA |
| EP(2)310 | 84 (139) | 100 (120) | 55B | polyA-binding protein (pAbp) | RNA-binding protein |
| EP(2)2235 | 98 (179) | 100 (175) | 39A | βν-integrin (βInt-ν) | Heterophilic cell adhesion molecule |
The results of a screen for Enhancer P (EP) mutations that suppress the behavioral bang-sensitive phenotype of eas are presented. The flies tested (Test) were males of the genotype eas; EP/+; elav-GAL4/+. Control flies of the genotype eas; +/CyO; elav-GAL4/+ were male siblings of the test flies. Test and control flies resulted from crosses between eas; elav-GAL4 virgin females and w; EP/CyO males. The number of flies tested is shown for each EP line. Results for the five EP lines that produced a highly significant (P < 0.001) fraction of non-bang-sensitive test progeny are shown in the first five rows; results for an additional line that produced a small but significant (P < 0.05) fraction of non-bang-sensitive test progeny is shown in the last row. The cytological map position of each EP insertion is given. When known, the corresponding gene and its molecular function are noted. NA, not applicable.