Abstract
We assessed the mortality rates by age, sex, race, blood type, primary diagnosis, treatment and transplantation history of 8432 patients in Canada for whom end-stage renal disease (ESRD) was diagnosed between 1981 and 1986. Significant differences in the probability of dying were found between those with and without diabetes mellitus, between those who had received a renal transplant and those who had not, between white and nonwhite patients and between various age groups. The mortality rates of the ESRD patients were at least three times higher than those of the general Canadian population. Primary diagnosis and treatment were significantly associated with the risk of dying among the ESRD patients. For those who had received a transplant, the length of time spent waiting for a transplant was positively associated with the risk of death from ESRD. Patients who had received peritoneal dialysis before transplantation had a higher risk of death than those who had received either hemodialysis (risk ratio 1.3) or transplantation (risk ratio 3.2) as the first treatment. No significant differences were found in the cause of death between those who had received peritoneal dialysis and those who had received hemodialysis. Almost half of the deaths among women without diabetes who had received a transplant were due to infection.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Garcia-Garcia G., Deddens J. A., D'Achiardi-Rey R., First M. R., Samuels S. J., Kant S., Pollak V. E. Results of treatment in patients with end-stage renal disease: a multivariate analysis of risk factors and survival in 341 successive patients. Am J Kidney Dis. 1985 Jan;5(1):10–18. doi: 10.1016/s0272-6386(85)80129-3. [DOI] [PubMed] [Google Scholar]
- Held P. J., Pauly M. V., Diamond L. Survival analysis of patients undergoing dialysis. JAMA. 1987 Feb 6;257(5):645–650. [PubMed] [Google Scholar]
- Hellerstedt W. L., Johnson W. J., Ascher N., Kjellstrand C. M., Knutson R., Shapiro F. L., Sterioff S. Survival rates of 2,728 patients with end-stage renal disease. Mayo Clin Proc. 1984 Nov;59(11):776–783. doi: 10.1016/s0025-6196(12)65589-x. [DOI] [PubMed] [Google Scholar]
- Higgins M. R., Grace M., Dossetor J. B. Survival of patients treated for end-stage renal disease by dialysis and transplantation. Can Med Assoc J. 1977 Oct 22;117(8):880–883. [PMC free article] [PubMed] [Google Scholar]
- Krakauer H., Grauman J. S., McMullan M. R., Creede C. C. The recent U.S. experience in the treatment of end-stage renal disease by dialysis and transplantation. N Engl J Med. 1983 Jun 30;308(26):1558–1563. doi: 10.1056/NEJM198306303082603. [DOI] [PubMed] [Google Scholar]
- Price J. D., Ashby K. M., Reeve C. E. Results of 12 years' treatment of chronic renal failure by dialysis and transplantation. Can Med Assoc J. 1978 Feb 4;118(3):263–266. [PMC free article] [PubMed] [Google Scholar]
- Rostand S. G., Kirk K. A., Rutsky E. A., Pate B. A. Racial differences in the incidence of treatment for end-stage renal disease. N Engl J Med. 1982 May 27;306(21):1276–1279. doi: 10.1056/NEJM198205273062106. [DOI] [PubMed] [Google Scholar]
- Umen A. J., Le C. T. Prognostic factors, models and related statistical problems in the survival of endstage renal disease patients on hemodialysis. Stat Med. 1986 Nov-Dec;5(6):637–652. doi: 10.1002/sim.4780050611. [DOI] [PubMed] [Google Scholar]