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. 1985 Feb;54(2):333–341.

Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor.

W A Jefferies, M R Brandon, A F Williams, S V Hunt
PMCID: PMC1453509  PMID: 2981766

Abstract

A mouse monoclonal IgG2a antibody, designated MRC OX-26, is shown to be specific for the rat transferrin receptor, but does not block transferrin binding. The antibody labelled a myeloma, three leukaemia cell lines and normal dividing cells of various types, but also bound to a number of nondividing normal tissues. No labelling of lymphopoietic stem cells could be detected, even though approximately 25% of bone marrow and over 95% of fetal liver cells were clearly labelled.

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Selected References

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