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. 1985 May;55(1):7–13.

Isolation of labile Fcgamma-receptors from human peripheral blood lymphocytes and production of an antiserum.

G P Sandilands, M G Peel, K S Froebel, J J Belch, R N MacSween
PMCID: PMC1453587  PMID: 3158596

Abstract

In this study, we have isolated membranelabile Fcgamma-receptors (i.e. FcgammaR I) from normal human peripheral blood lymphocytes and have produced a rabbit antiserum to this protein. Using this antiserum, we have shown that membrane-labile and membrane-stable (i.e. FcgammaR II) Fcgamma-receptors are antigenically distinct and that these two forms of the receptors probably coexist on the same lymphocyte subpopulation. Moreover, it was apparent that lymphocyte FcgammaR Is are distinct from FcgammaRs expressed on other cell types (e.g. monocytes, polymorphs and spermatozoa). Preliminary evidence does suggest, however, that human platelets express an FcgammaR which is antigenically similar to human lymphocyte FcgammaR I.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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