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. 1985 Oct;56(2):295–300.

Quantitative relationship between T3 and the T-cell antigen receptor on a human leukaemic line.

R D Goldin, R A Boulton, A W Boylston
PMCID: PMC1453702  PMID: 3863788

Abstract

The T-cell antigen receptor complex consists of an idiotypic molecule, Ti, and T3. We have investigated the relationship between Ti and T3 on a leukaemic line HPB-ALL. This has shown that the two molecules are expressed on the cell surface in equal numbers, and that a similar stoichiometric relationship is seen on sublines of HPB-ALL selected for diminished expression of Ti. Furthermore, the degrees of modulation and rates of resynthesis of Ti and T3 following modulation were very similar, regardless of whether anti-Ti or anti-T3 was used to produce the modulation. This work strongly suggests that the expression of Ti and T3 are under common control.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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