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. 1987 Sep;62(1):149–151.

Stimulation of neutrophil respiratory burst and lysosomal enzyme release by human interferon-gamma.

I C Kowanko 1, A Ferrante 1
PMCID: PMC1453728  PMID: 3115891

Abstract

Highly purified human interferon-gamma (IFN-gamma) induced a respiratory burst and lysosomal enzyme release in human neutrophils. The lymphokine augmented the respiratory burst induced by phorbol myristate acetate (PMA), or N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), and increased the release of specific granule enzymes induced by opsonized zymosan. Viability and locomotion of neutrophils were unaffected by IFN-gamma.

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Selected References

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