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. 1983 Feb;48(2):401–409.

Molecular distribution of preformed thyroglobulin immune complexes.

S Husby, J Steensgaard, U Feldt-Rasmussen, J Date
PMCID: PMC1453933  PMID: 6822408

Abstract

Thyroglobulin anti-thyroglobulin immune complexes with human antibodies from four patient sera were performed in a wide range of antigen: antibody ratios and run in 5%-40% sucrose gradients. The fractionation showed simple distributions of thyroglobulin molecules in immune complexes, especially in far antigen and far antibody excess. A computer simulation analysis which utilized the experimental presumptions and assumed an association constant in the order of 10(9), showed a large degree of similarity to the experimental results. Thus, a thermodynamically simple explanation of immune complex formation did not contradict the experimental thyroglobulin anti-thyroglobulin complex formation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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