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. 1987 Oct;62(2):329–331.

Endometrial granulocytes in human decidua react with a natural-killer (NK) cell marker, NKH1.

A Ritson 1, J N Bulmer 1
PMCID: PMC1453990  PMID: 3315980

Abstract

Lymphoid cells in decidualized uterine endometrium in early human pregnancy may be essential for successful implantation and placentation. Endometrial granulocytes are prominent in early pregnancy decidua and express some T-cell associated surface antigens (CD2+, CD7+), but little is known of their function. We report the unusually intense binding of the natural-killer (NK) cell marker NKH1 to endometrial granulocytes, which contrasts with their lack of reactivity with other NK-cell markers.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bulmer J. N., Johnson P. M. Macrophage populations in the human placenta and amniochorion. Clin Exp Immunol. 1984 Aug;57(2):393–403. [PMC free article] [PubMed] [Google Scholar]
  2. Bulmer J. N., Johnson P. M. The T-lymphocyte population in first-trimester human decidua does not express the interleukin-2 receptor. Immunology. 1986 Aug;58(4):685–687. [PMC free article] [PubMed] [Google Scholar]
  3. Bulmer J. N., Sunderland C. A. Bone-marrow origin of endometrial granulocytes in the early human placental bed. J Reprod Immunol. 1983 Nov;5(6):383–387. doi: 10.1016/0165-0378(83)90247-4. [DOI] [PubMed] [Google Scholar]
  4. Bulmer J. N., Sunderland C. A. Immunohistological characterization of lymphoid cell populations in the early human placental bed. Immunology. 1984 Jun;52(2):349–357. [PMC free article] [PubMed] [Google Scholar]
  5. Clark D. A., Slapsys R., Chaput A., Walker C., Brierley J., Daya S., Rosenthal K. L. Immunoregulatory molecules of trophoblast and decidual suppressor cell origin at the maternofetal interface. Am J Reprod Immunol Microbiol. 1986 Mar;10(3):100–104. [PubMed] [Google Scholar]
  6. Croy B. A., Gambel P., Rossant J., Wegmann T. G. Characterization of murine decidual natural killer (NK) cells and their relevance to the success of pregnancy. Cell Immunol. 1985 Jul;93(2):315–326. doi: 10.1016/0008-8749(85)90137-6. [DOI] [PubMed] [Google Scholar]
  7. Daya S., Clark D. A., Devlin C., Jarrell J. Preliminary characterization of two types of suppressor cells in the human uterus. Fertil Steril. 1985 Dec;44(6):778–785. doi: 10.1016/s0015-0282(16)49037-0. [DOI] [PubMed] [Google Scholar]
  8. Lanier L. L., Le A. M., Civin C. I., Loken M. R., Phillips J. H. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol. 1986 Jun 15;136(12):4480–4486. [PubMed] [Google Scholar]

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