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. 1983 Sep;50(1):113–120.

Purification and characterization of excretory and secretory antigen of Toxocara canis larvae.

K Sugane, T Oshima
PMCID: PMC1454224  PMID: 6411609

Abstract

Excretory/secretory (ES) antigen of Toxocara canis larvae was isolated from the culture medium of second-stage larvae by gel filtration. The antigen induced production of not only IgM or IgG but also IgE antibody. The antigen, when treated with guanidine hydrochloride and 2-mercaptoethanol, lost its allergenic activity but retained an ability to induce IgM or IgG antibody. Purified antigen was of glycoprotein nature and had a molecular weight of 35,000. The whole antigen showed a cross-reaction with the serum from Ascaris suum-infected mice. The antigen did not contain phosphorylcholine as a structural component.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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