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. 1984 Jul;52(3):457–468.

Class 1 major histocompatibility complex antigens on human extra-villous trophoblast.

C W Redman, A J McMichael, G M Stirrat, C A Sunderland, A Ting
PMCID: PMC1454489  PMID: 6204930

Abstract

Using immunohistological techniques, class 1 products of the major histocompatibility complex (MHC) have been demonstrated on various forms of human extra-villous trophoblast in placental tissues taken from first, second and third trimester pregnancies. This contrasts with the absence of class 1 MHC antigens on all forms of villous trophoblast. The extra-villous trophoblast which reacted with antibodies to monomorphic class 1 MHC antigens consistently failed to bind HLA-A or HLA-B antibodies specific for the foetal phenotype. This suggests, but does not prove, that the MHC antigen expression of trophoblast may be restricted to HLA-C or some other undefined class 1 antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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