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. 1984 Oct;53(2):299–305.

Generation of slow-reacting substance (leukotrienes) by endotoxin and lipid A from human polymorphonuclear granulocytes.

K D Bremm, W König, B Spur, A Crea, C Galanos
PMCID: PMC1454833  PMID: 6490085

Abstract

Leukotrienes were released from human polymorphonuclear granulocytes on incubation with endotoxins and lipid A. The analysis was performed by their smooth muscle contracting properties, reversed phase high-pressure liquid chromatography and radioimmunoassay for leukotrienes C4 and D4. The active component of the lipopolysaccharides seems to be the lipid A portion.

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Selected References

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