Abstract
Rabbit circulating lymphocytes have been examined for the a locus allotypic markers As1, As2 and As3 using the mixed antiglobulin reaction. These determinants cannot be as easily demonstrated as the b locus determinants As4, As5 and As6. Undiluted antiserum is required and even then the percentage of reacting cells is low. The specificity of the reaction was checked by an inhibition procedure.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Coombs R. R., Gurner B. W., Janeway C. A., Jr, Wilson A. B., Gell P. G., Kelus A. S. Immunoglobulin determinants on the lymphocytes of normal rabbits. I. Demonstration by the mixed antiglobulin reaction of determinants recognized by anti-gamma, anti-mu, anti-Fab and anti-allotype sera, anti-As4 and anti-As6. Immunology. 1970 Mar;18(3):417–429. [PMC free article] [PubMed] [Google Scholar]
- Dubiski S. Immunochemistry and genetics of a "new" allotypic specificity Ae14 of rabbit gamma-G immunoglobulins: recombination in somatic cells. J Immunol. 1969 Jul;103(1):120–128. [PubMed] [Google Scholar]
- Kelus A. S., Gell P. G. Immunoglobulin allotypes of experimental animals. Prog Allergy. 1967;11:141–184. [PubMed] [Google Scholar]
- Mandy W. J., Todd C. W. Allotypy of rabbit immunoglobulin: an agglutinating specificity. Vox Sang. 1968;14(4):264–270. doi: 10.1111/j.1423-0410.1968.tb04622.x. [DOI] [PubMed] [Google Scholar]
