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. 1971 May;20(5):809–815.

The natural mediator for PMN emigration in inflammation

III. In vitro production of a chemotactic factor by inflammatory SH-dependent protease from serum immunoglobulin G

M Yoshinaga, S Yamamoto, S Maeda, H Hayashi
PMCID: PMC1455879  PMID: 4137989

Abstract

In earlier work, a chemotactic factor (leucoegresin) specific for polymorphonuclear (PMN) leucocytes had been isolated from the sites of Arthus reactions or cutaneous burns. The substance shared antigenic sites with IgG.

The possible existence precursor of the chemotactic factor in the γ2-globulin fraction of normal rabbit sera is suggested since the protein fraction on incubation with a purified neutral SH-dependent protease from inflammatory tissue became strongly chemotactic.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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