Skip to main content
NCBI home page
Immunology logoLink to Immunology
. 1969 Dec;17(6):991–994.

Immunological evidence for human myosin isoenzymes

Ute Gröschel-Stewart, Deborah Doniach
PMCID: PMC1456031  PMID: 4247956

Abstract

Antibodies produced in rabbits against purified human pectoralis actomyosin reacted only with `red fibres' in striated muscle and cardiac muscle, suggesting antigenic differences between `red' and `white' actomyosins. There was no cross-reaction with smooth muscle actomyosin.

Full text

PDF
991

Images in this article

992FIG. 1
on p.992

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARANY M., BARANY K., RECKARD T., VOLPE A. MYOSIN OF FAST AND SLOW MUSCLES OF THE RABBIT. Arch Biochem Biophys. 1965 Jan;109:185–191. doi: 10.1016/0003-9861(65)90304-8. [DOI] [PubMed] [Google Scholar]
  2. Beutner E. H., Fazekas G., Scott A., Witebsky E. Direct fluorescent antibody studies of gamma globulin localization in muscle of patients with myasthenia gravis. Ann N Y Acad Sci. 1966 Jan 26;135(1):588–600. doi: 10.1111/j.1749-6632.1966.tb45506.x. [DOI] [PubMed] [Google Scholar]
  3. Bárány M. ATPase activity of myosin correlated with speed of muscle shortening. J Gen Physiol. 1967 Jul;50(6 Suppl):197–218. doi: 10.1085/jgp.50.6.197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DUBOWITZ V., PEARSE A. G. A comparative histochemical study of oxidative enzyme and phosphorylase activity in skeletal muscle. Z Zellforch Microsk Anat Histochem. 1960;2:105–117. doi: 10.1007/BF00744575. [DOI] [PubMed] [Google Scholar]
  5. Doniach D., Roitt I. M., Walker J. G., Sherlock S. Tissue antibodies in primary biliary cirrhosis, active chronic (lupoid) hepatitis, cryptogenic cirrhosis and other liver diseases and their clinical implications. Clin Exp Immunol. 1966 Jul;1(3):237–262. [PMC free article] [PubMed] [Google Scholar]
  6. FURMINGER I. G. THE ANTIGENIC CONSTITUENTS OF MYOSIN PREPARATIONS. Biochim Biophys Acta. 1964 Sep 4;90:521–533. doi: 10.1016/0304-4165(64)90231-4. [DOI] [PubMed] [Google Scholar]
  7. Feltkamp T. E., Feltkamp-Vroom T. M. Antibodies against the various types of skeletal muscle fibres. Immunology. 1965 Sep;9(3):275–279. [PMC free article] [PubMed] [Google Scholar]
  8. Finck H. Immunochemical studies on myosin. IV. Immunochemical comparison of rabbit and chicken skeletal muscle myosins. Biochim Biophys Acta. 1965 Nov 15;111(1):239–246. [PubMed] [Google Scholar]
  9. Fox A. C., Klein M. D. An immunochemical comparison of myosin from canine heart and skeletal muscle. Biochim Biophys Acta. 1966 Sep 26;127(1):232–235. doi: 10.1016/0304-4165(66)90493-4. [DOI] [PubMed] [Google Scholar]
  10. Johnson G. D., Holborow E. J., Glynn L. E. Antibody to smooth muscle in patients with liver disease. Lancet. 1965 Oct 30;2(7418):878–879. doi: 10.1016/s0140-6736(65)92505-5. [DOI] [PubMed] [Google Scholar]
  11. Locker R. H., Hagyard C. J. The myosin of rabbit red muscles. Arch Biochem Biophys. 1968 Sep 20;127(1):370–375. doi: 10.1016/0003-9861(68)90238-5. [DOI] [PubMed] [Google Scholar]
  12. Ricken D. Myasthenia gravis and humoral antibodies against human skeletal muscle proteins. Ger Med Mon. 1966 Apr;11(4):134–138. [PubMed] [Google Scholar]
  13. SAMUELS A. The immuno-enzymology of muscle proteins. I. General features of myosin and 5'-adenylic acid deaminase. Arch Biochem Biophys. 1961 Mar;92:497–506. doi: 10.1016/0003-9861(61)90390-3. [DOI] [PubMed] [Google Scholar]
  14. Sreter F. A., Seidel J. C., Gergely J. Studies on myosin from red and white skeletal muscles of the rabbit. I. Adenosine triphosphatase activity. J Biol Chem. 1966 Dec 25;241(24):5772–5776. [PubMed] [Google Scholar]
  15. Strauss A. J., Kemp P. G., Jr Serum autoantibodies in myasthenia gravis and thymoma: selective affinity for I-bands of striated muscle as a guide to identification of antigen(s). J Immunol. 1967 Nov;99(5):945–953. [PubMed] [Google Scholar]
  16. Syrový I. Studies on proteolytic digestion of myosin from red and white skeletal muscles of the rabbit. Experientia. 1968 Nov 15;24(11):1108–1108. doi: 10.1007/BF02147785. [DOI] [PubMed] [Google Scholar]
  17. Wu C. S. Comparative studies on myosins from breast and leg muscles of chicken. Biochemistry. 1969 Jan;8(1):39–48. doi: 10.1021/bi00829a007. [DOI] [PubMed] [Google Scholar]

Articles from Immunology are provided here courtesy of British Society for Immunology

RESOURCES