TABLE 4.
Genetic interactions of arp2 alleles with arc35 alleles
| Genotype | 25° | 30° | 34° | 37° | Genetic interaction |
|---|---|---|---|---|---|
| Haploid | |||||
| ARP2, ARC35 | +++ | +++ | +++ | +++ | NA |
| arp2-1, ARC35 | +++ | ++ | + | − | NA |
| arp2-7, ARC35 | +++ | ++ | + | − | NA |
| ARP2, arc35-5 | +++ | +++ | ++ | ++ | NA |
| ARP2, arc35-6 | +++ | +++ | +++ | +++ | NA |
| arp2-1, arc35-5 | ++ | ++ | − | − | NE/SS |
| arp2-7, arc35-5 | − | − | − | − | SL |
| arp2-1, arc35-6 | ++ | − | − | − | SS |
| arp2-7, arc35-6 | +++ | ++ | + | − | NE |
| Diploid | |||||
| ARP2/ARP2 | +++ | +++ | +++ | +++ | NA |
| arp2-1/ARP2 | +++ | +++ | +++ | +++ | Recessive |
| arp2-7/ARP2 | +++ | +++ | +++ | +++ | Recessive |
| arp2-1/arp2-1 | +++ | ++ | + | − | NA |
| arp2-7/arp2-7 | +++ | ++ | + | − | NA |
| arp2-1/arp2-7 | +++ | ++ | + | − | NE |
Relative growth of yeast strains is expressed as +++, wild type; ++, partially compromised; +, severely compromised; and −, no growth. NA, not applicable; NE, no effect; SL, synthetic lethal; SS, synthetic sick.