Abstract
The participation of cell subpopulations in the expression of leucocyte migration inhibition factor (LMIF) in response to Concanavalin A and Protein A was evaluated for cells isolated from the peripheral blood of five healthy subjects. LMIF activity could not be attributed to the function of T cells, B enriched cells, or monocytes acting alone, or to a combination of B enriched cells and monocytes. The LMIF response was the result of a collaborative event that occurred between T cells and B enriched cells, or between T cells and monocytes.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl. 1968;97:77–89. [PubMed] [Google Scholar]
- Chess L., Rocklin R. E., MacDermott R. P., David J. R., Schlossman S. F. Leukocyte inhibitory factor (LIF): production by purified human T and B lymphocytes. J Immunol. 1975 Jul;115(1):315–317. [PubMed] [Google Scholar]
- Horwitz D. A., Lobo P. I. Characterizaiton of two populations of human lymphocytes bearing easily detectable surface immunoglobulin. J Clin Invest. 1975 Dec;56(6):1464–1472. doi: 10.1172/JCI108227. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pick E., Godny Y., Gold E. F. Participation of immunoglobulin-bearing lymphocytes in the production of macrophage migration inhibitory factor. Eur J Immunol. 1975 Aug;5(8):584–587. doi: 10.1002/eji.1830050816. [DOI] [PubMed] [Google Scholar]
- Rocklin R. E. Products of activated lymphocytes: leukocyte inhibitory factor (LIF) distinct from migration inhibitory factor (MIF). J Immunol. 1974 Apr;112(4):1461–1466. [PubMed] [Google Scholar]
- Weisbart R. H., Mickey M. R. A microassay for leukocyte migration: analysis of its reproducibility. J Immunol Methods. 1977;16(3):269–281. doi: 10.1016/0022-1759(77)90204-6. [DOI] [PubMed] [Google Scholar]
- Yu D. T., Ramer S. J., Kacena A. Effect of corticosteroids on the response of lymphocytes to stimulation by galactose oxidase-modified lymphocytes. Immunology. 1977 Aug;33(2):247–252. [PMC free article] [PubMed] [Google Scholar]