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. 1980 Apr;39(4):599–605.

Inhibition or killing of an intracellular pathogen by activated macrophages is abrogated by TLCK or aminophylline.

R McLeod, J S Remington
PMCID: PMC1458029  PMID: 7380481

Abstract

Agents that are known to inhibit certain metabolic pathways or cell functions were evaluated to determine their effects on the capacity of activated macrophages to inhibit or kill obligate intracellular pathogens. Tosyllysine chloromethyl ketone (TLCK) and aminophylline abrogate inhibition or killing of Toxoplasma gondii by activated macrophages.

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Selected References

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