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. 1980 Oct;41(2):387–392.

Characterization of the cytotoxic factor produced in the spleen of dengue virus-infected mice.

U C Chaturvedi, H Dalakoti, A Mathur
PMCID: PMC1458193  PMID: 7439933

Abstract

Data presented in the study show that the cytotoxic factor (CF) produced in the spleen of (dengue-virus) infected mice can be purified by agarose-gel electrophoresis and Sephadex G-100 gel filtration. CF is non-dialysable, heat-labile, trypsin-sensitive, unstable at acidic and alkaline pH, a macromolecular substance which sediments on ultracentrifugation and is retained by a Millipore filter of 0.45 micron size. Its approximate molecular weight is 1.15 (+/- 0.34) x 10(5) as determined by gel filtration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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