Skip to main content
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1996 May 1;24(9):1787–1788. doi: 10.1093/nar/24.9.1787

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.

M Schorpp 1, R Jäger 1, K Schellander 1, J Schenkel 1, E F Wagner 1, H Weiher 1, P Angel 1
PMCID: PMC145851  PMID: 8650001

Full Text

The Full Text of this article is available as a PDF (45.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Angel P., Hattori K., Smeal T., Karin M. The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell. 1988 Dec 2;55(5):875–885. doi: 10.1016/0092-8674(88)90143-2. [DOI] [PubMed] [Google Scholar]
  2. Ciechanover A., Finley D., Varshavsky A. The ubiquitin-mediated proteolytic pathway and mechanisms of energy-dependent intracellular protein degradation. J Cell Biochem. 1984;24(1):27–53. doi: 10.1002/jcb.240240104. [DOI] [PubMed] [Google Scholar]
  3. Fanidi A., Harrington E. A., Evan G. I. Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature. 1992 Oct 8;359(6395):554–556. doi: 10.1038/359554a0. [DOI] [PubMed] [Google Scholar]
  4. Furth P. A., Hennighausen L., Baker C., Beatty B., Woychick R. The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Res. 1991 Nov 25;19(22):6205–6208. doi: 10.1093/nar/19.22.6205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hershko A., Ciechanover A. Mechanisms of intracellular protein breakdown. Annu Rev Biochem. 1982;51:335–364. doi: 10.1146/annurev.bi.51.070182.002003. [DOI] [PubMed] [Google Scholar]
  6. McBurney M. W., Staines W. A., Boekelheide K., Parry D., Jardine K., Pickavance L. Murine PGK-1 promoter drives widespread but not uniform expression in transgenic mice. Dev Dyn. 1994 Aug;200(4):278–293. doi: 10.1002/aja.1002000403. [DOI] [PubMed] [Google Scholar]
  7. Ryder K., Lau L. F., Nathans D. A gene activated by growth factors is related to the oncogene v-jun. Proc Natl Acad Sci U S A. 1988 Mar;85(5):1487–1491. doi: 10.1073/pnas.85.5.1487. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Rüther U., Müller W., Sumida T., Tokuhisa T., Rajewsky K., Wagner E. F. c-fos expression interferes with thymus development in transgenic mice. Cell. 1988 Jun 17;53(6):847–856. doi: 10.1016/s0092-8674(88)90289-9. [DOI] [PubMed] [Google Scholar]
  9. Sands A. T., Hansen T. N., Demayo F. J., Stanley L. A., Xin L., Schwartz R. J. Cytoplasmic beta-actin promoter produces germ cell and preimplantation embryonic transgene expression. Mol Reprod Dev. 1993 Feb;34(2):117–126. doi: 10.1002/mrd.1080340202. [DOI] [PubMed] [Google Scholar]
  10. Schmidt E. V., Christoph G., Zeller R., Leder P. The cytomegalovirus enhancer: a pan-active control element in transgenic mice. Mol Cell Biol. 1990 Aug;10(8):4406–4411. doi: 10.1128/mcb.10.8.4406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Wiborg O., Pedersen M. S., Wind A., Berglund L. E., Marcker K. A., Vuust J. The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences. EMBO J. 1985 Mar;4(3):755–759. doi: 10.1002/j.1460-2075.1985.tb03693.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Wulff B. S., O'Hare M. M., Boel E., Theill L. E., Schwartz T. W. Partial processing of the neuropeptide Y precursor in transfected CHO cells. FEBS Lett. 1990 Feb 12;261(1):101–105. doi: 10.1016/0014-5793(90)80646-z. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES