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. 1996 Jun 15;24(12):2456–2457. doi: 10.1093/nar/24.12.2456

The use of alpha-DNA as an internal standard in the detection and quantitation of DNA damage in specific genes using Southern blotting.

A Sunters 1, K A Grimaldi 1, R L Souhami 1, J A Hartley 1
PMCID: PMC145939  PMID: 8710523

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Selected References

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  1. Bohr V. A., Smith C. A., Okumoto D. S., Hanawalt P. C. DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell. 1985 Feb;40(2):359–369. doi: 10.1016/0092-8674(85)90150-3. [DOI] [PubMed] [Google Scholar]
  2. Grimaldi K. A., Bingham J. P., Souhami R. L., Hartley J. A. DNA damage by anticancer agents and its repair: mapping in cells at the subgene level with quantitative polymerase chain reaction. Anal Biochem. 1994 Oct;222(1):236–242. doi: 10.1006/abio.1994.1479. [DOI] [PubMed] [Google Scholar]
  3. Hall A., Brown R. Human N-ras: cDNA cloning and gene structure. Nucleic Acids Res. 1985 Jul 25;13(14):5255–5268. doi: 10.1093/nar/13.14.5255. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kroczek R. A. Southern and northern analysis. J Chromatogr. 1993 Aug 25;618(1-2):133–145. doi: 10.1016/0378-4347(93)80031-x. [DOI] [PubMed] [Google Scholar]
  5. Larminat F., Bohr V. A. Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage. Nucleic Acids Res. 1994 Aug 11;22(15):3005–3010. doi: 10.1093/nar/22.15.3005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Wassermann K., Kohn K. W., Bohr V. A. Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells. J Biol Chem. 1990 Aug 15;265(23):13906–13913. [PubMed] [Google Scholar]
  7. Wu J. C., Manuelidis L. Sequence definition and organization of a human repeated DNA. J Mol Biol. 1980 Sep 25;142(3):363–386. doi: 10.1016/0022-2836(80)90277-6. [DOI] [PubMed] [Google Scholar]
  8. Zhen W., Evans M. K., Haggerty C. M., Bohr V. A. Deficient gene specific repair of cisplatin-induced lesions in Xeroderma pigmentosum and Fanconi's anemia cell lines. Carcinogenesis. 1993 May;14(5):919–924. doi: 10.1093/carcin/14.5.919. [DOI] [PubMed] [Google Scholar]

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