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. 1984;18(Suppl 1):73S–82S. doi: 10.1111/j.1365-2125.1984.tb02584.x

Saccadic eye movement analysis as a measure of drug effects on human psychomotor performance

A N Griffiths, R W Marshall, A Richens
PMCID: PMC1463359  PMID: 6151850

Abstract

1 Analysis of human horizontal saccadic eye movements can provide measurements of central nervous system depression and stimulation.

2 Effects on saccadic eye movements have been observed in normal volunteers with barbiturates, benzodiazepines, opiates and related compounds, carbamazepine, amphetamine and ethanol.

3 A suite of programmes have been developed to allow the generation, collection and analysis of saccadic eye movements using a CBM 3032, 8032 or BBC B microcomputer. The system allows almost continuous sampling and rapid analysis of movements.

Keywords: eye movements, saccades, psychomotor testing, benzodiazepines ethanol, amphetamine, microcomputers

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Selected References

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