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. 1997 Jan 1;25(1):269–271. doi: 10.1093/nar/25.1.269

MHCPEP, a database of MHC-binding peptides: update 1996.

V Brusic 1, G Rudy 1, A P Kyne 1, L C Harrison 1
PMCID: PMC146366  PMID: 9016551

Abstract

MHCPEP is a curated database comprising over 9000 peptide sequences known to bind MHC molecules. Entries are compiled from published reports as well as from direct submissions of experimental data. Each entry contains the peptide sequence, its MHC specificity and, when available, experimental method, observed activity, binding affinity, source protein, anchor positions and publication references. The present format of the database allows text string matching searches but can easily be converted for use in conjunction with sequence analysis packages. The database can be accessed via Internet using WWW, FTP or Gopher.

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Selected References

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  1. Bairoch A., Apweiler R. The SWISS-PROT protein sequence data bank and its new supplement TREMBL. Nucleic Acids Res. 1996 Jan 1;24(1):21–25. doi: 10.1093/nar/24.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bodmer J. G., Marsh S. G., Albert E. D., Bodmer W. F., Bontrop R. E., Charron D., Dupont B., Erlich H. A., Mach B., Mayr W. R. Nomenclature for factors of the HLA system, 1995. Hum Immunol. 1995 Jun;43(2):149–164. doi: 10.1016/0198-8859(95)00071-b. [DOI] [PubMed] [Google Scholar]
  3. Brusic V., Rudy G., Harrison L. C. MHCPEP: a database of MHC-binding peptides. Nucleic Acids Res. 1994 Sep;22(17):3663–3665. doi: 10.1093/nar/22.17.3663. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Brusic V., Rudy G., Kyne A. P., Harrison L. C. MHCPEP--a database of MHC-binding peptides: update 1995. Nucleic Acids Res. 1996 Jan 1;24(1):242–244. doi: 10.1093/nar/24.1.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Chicz R. M., Urban R. G., Gorga J. C., Vignali D. A., Lane W. S., Strominger J. L. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med. 1993 Jul 1;178(1):27–47. doi: 10.1084/jem.178.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Etzold T., Argos P. SRS--an indexing and retrieval tool for flat file data libraries. Comput Appl Biosci. 1993 Feb;9(1):49–57. doi: 10.1093/bioinformatics/9.1.49. [DOI] [PubMed] [Google Scholar]
  7. George D. G., Barker W. C., Mewes H. W., Pfeiffer F., Tsugita A. The PIR-International Protein Sequence Database. Nucleic Acids Res. 1996 Jan 1;24(1):17–20. doi: 10.1093/nar/24.1.17. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hammer J., Valsasnini P., Tolba K., Bolin D., Higelin J., Takacs B., Sinigaglia F. Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell. 1993 Jul 16;74(1):197–203. doi: 10.1016/0092-8674(93)90306-b. [DOI] [PubMed] [Google Scholar]
  9. Klein J., Bontrop R. E., Dawkins R. L., Erlich H. A., Gyllensten U. B., Heise E. R., Jones P. P., Parham P., Wakeland E. K., Watkins D. I. Nomenclature for the major histocompatibility complexes of different species: a proposal. Immunogenetics. 1990;31(4):217–219. doi: 10.1007/BF00204890. [DOI] [PubMed] [Google Scholar]
  10. Rammensee H. G., Friede T., Stevanoviíc S. MHC ligands and peptide motifs: first listing. Immunogenetics. 1995;41(4):178–228. doi: 10.1007/BF00172063. [DOI] [PubMed] [Google Scholar]

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