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. 2000 May;196(Pt 4):543–554. doi: 10.1046/j.1469-7580.2000.19640543.x

Imaging basal ganglia function

DAVID J BROOKS 1,✉
PMCID: PMC1468096  PMID: 10923986

Abstract

In this review, the value of functional imaging for providing insight into the role of the basal ganglia in motor control is reviewed. Brain activation findings in normal subjects and Parkinson's disease patients are examined and evidence supporting the existence for functionally independent distributed basal ganglia-frontal loops is presented. It is argued that the basal ganglia probably act to focus and filter cortical output, optimising the running of motor programs.

Keywords: Motor control, Parkinson's disease, positron emission tomography

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Selected References

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