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. 1997 Jul 15;25(14):2943–2944. doi: 10.1093/nar/25.14.2943

Avoidance of sulfur loss during ammonia treatment of oligonucleotide phosphorothioates.

C B Reese 1, Q Song 1
PMCID: PMC146813  PMID: 9207048

Abstract

Sulfur loss during the unblocking of phosphorothioate analogues of oligonucleotides with concentrated aqueous ammonia can be completely suppressed by the addition of 2-mercaptoethanol.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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