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. 1971 Jun;8(2):215–219. doi: 10.1136/jmg.8.2.215

A case of XYY Down's syndrome confirmed by autoradiography.

R Laxova, J A McKeown, P Saldaña, J A Timothy
PMCID: PMC1469004  PMID: 4255423

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BECKER K. L., BURKE E. C., ALBERT A. Double autosomal trisomy (D trisomy plus mongolism). Proc Staff Meet Mayo Clin. 1963 Jun 5;38:242–248. [PubMed] [Google Scholar]
  2. Brown W. M. Males with an XYY sex chromosome complement. J Med Genet. 1968 Dec;5(4):341–359. doi: 10.1136/jmg.5.4.341. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DAY R. W., WRIGHT S. W., KOONS A., QUIGLEY M. XXX 21-trisomy and retinoblastoma. Lancet. 1963 Jul 20;2(7299):154–155. doi: 10.1016/s0140-6736(63)92629-1. [DOI] [PubMed] [Google Scholar]
  4. FORD C. E., JONES K. W., MILLER O. J., MITTWOCH U., PENROSE L. S., RIDLER M., SHAPIRO A. The chromosomes in a patient showing both mongolism and the Klinefelter syndrome. Lancet. 1959 Apr 4;1(7075):709–710. doi: 10.1016/s0140-6736(59)91891-4. [DOI] [PubMed] [Google Scholar]
  5. FORSSMAN H., LEHMANN O. Chromosome studies in eleven families with mongolism in more than one member. Acta Paediatr. 1962 Mar;51:180–188. doi: 10.1111/j.1651-2227.1962.tb06527.x. [DOI] [PubMed] [Google Scholar]
  6. Forssman H., Akesson H. A., Wallin L. The YY syndrome. Lancet. 1968 Oct 5;2(7571):779–779. doi: 10.1016/s0140-6736(68)90986-0. [DOI] [PubMed] [Google Scholar]
  7. GAGNON J., KATYK-LONGTIN N., de GROOT J., BARBEAU A. [Double autosomal trisomy with 48 chromosomes (21 and 18)]. Union Med Can. 1961 Nov;90:1220–1226. [PubMed] [Google Scholar]
  8. GRIPENBERG U., AIRAKSINEN E. A D/F TRANSLOCATION IN A CASE OF REGULAR TRISOMY 21 DOWN'S SYNDROME. Cytogenetics. 1964;3:218–227. [PubMed] [Google Scholar]
  9. Glogowska I. Mozaika 47-48 u pacjenta z zespołem Downa. Neurol Neurochir Pol. 1969 May-Jun;3(3):263–266. [PubMed] [Google Scholar]
  10. HALL B. Down's syndrome (mongolism) with a morphological Philadelphia chromosome. Lancet. 1963 Mar 9;1(7280):558–558. doi: 10.1016/s0140-6736(63)91366-7. [DOI] [PubMed] [Google Scholar]
  11. HAMERTON J. L., JAGIELLO G. M., KIRMAN B. H. Sex-chromosome abnormalities in a population of mentally defective children. Br Med J. 1962 Jan 27;1(5273):220–223. doi: 10.1136/bmj.1.5273.220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HODGE J. V., NYE E. R., EMERSON G. W. MONOAMINE-OXIDASE INHIBITORS, BROAD BEANS, AND HYPERTENSION. Lancet. 1964 May 16;1(7342):1108–1108. doi: 10.1016/s0140-6736(64)91316-9. [DOI] [PubMed] [Google Scholar]
  13. HSU L. Y., SCHWANGER A. J., NEMHAUSER I., SOBEL E. H. A CASE OF DOUBLE AUTOSOMAL TRISOMY WITH MOSAICISM: 48/XX (TRISOMY 18+21) AND 46/XX. J Pediatr. 1965 Jun;66:1055–1060. doi: 10.1016/s0022-3476(65)80092-0. [DOI] [PubMed] [Google Scholar]
  14. HUSTINX T. W., EBERLE P., GEERTS S. J., ten BRINK, WOLTRING L. M. Mongoloid twins with 48 chromosomes (AA plus A21XXY). Ann Hum Genet. 1961 Oct;25:111–115. doi: 10.1111/j.1469-1809.1961.tb01507.x. [DOI] [PubMed] [Google Scholar]
  15. LANMAN J. T., SKLARIN B. S., COOPER H. L., HIRSCHHORN K. Klinefelter's syndrome in a ten-month-old mongolian idiot: report of a case with chromosome analysis. N Engl J Med. 1960 Nov 3;263:887–890. doi: 10.1056/NEJM196011032631804. [DOI] [PubMed] [Google Scholar]
  16. MILCOU S., MAICANESCO M. SYNDROME DE KLINEFELTER ASSOCI'E AU MONGOLISME ET 'A L'ECTOPIE TESTICULAIRE BILAT'ERALE. Pathol Biol. 1963 Nov;11:1247–1250. [PubMed] [Google Scholar]
  17. Marks J. F., Wiggins K. M., Spector B. J. Trisomy 21-trisomy 18 mosaicism in a boy with clinical Down's syndrome. J Pediatr. 1967 Jul;71(1):126–128. doi: 10.1016/s0022-3476(67)80243-9. [DOI] [PubMed] [Google Scholar]
  18. Marsden H. B., Mackay R. I., Murray A., Ward H. E. Down's syndrome with a familial D/D reciprocal translocation and a G/G chromosome. J Med Genet. 1966 Mar;3(1):56–58. doi: 10.1136/jmg.3.1.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Orye E., Delire C. Familial D/D and D/G, translocation. Helv Paediatr Acta. 1967 Apr;22(1):36–40. [PubMed] [Google Scholar]
  20. Penrose L. S. Finger-print pattern and the sex chromosomes. Lancet. 1967 Feb 11;1(7485):298–300. doi: 10.1016/s0140-6736(67)91237-8. [DOI] [PubMed] [Google Scholar]
  21. Penrose L. S., Loesch D. A study of dermal ridge width in the second (palmar) interdigital area with special reference to aneuploid states. J Ment Defic Res. 1967 Mar;11(1):36–42. doi: 10.1111/j.1365-2788.1967.tb00201.x. [DOI] [PubMed] [Google Scholar]
  22. Porter I. H., Petersen W., Brown C. D. Double autosomal trisomy (trisomy D+G) with mosaicism. J Med Genet. 1969 Sep;6(3):347–348. doi: 10.1136/jmg.6.3.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Price W. H., Whatmore P. B. Criminal behavior and the XYY male. Nature. 1967 Feb 25;213(5078):815–815. doi: 10.1038/213815a0. [DOI] [PubMed] [Google Scholar]
  24. RICHARDS B. W., STEWART A., SYLVESTER P. E. RECIPROCAL TRANSLOCATION AND MOSAICISM IN A MONGOL. J Ment Defic Res. 1965 Jun;9:118–124. doi: 10.1111/j.1365-2788.1965.tb00828.x. [DOI] [PubMed] [Google Scholar]
  25. RUFFIE J., DUCOS J., BIERME R., COLOMBIES P., SALLES-MOURLAN A. M. MULTIPLE CHROMOSOMAL ABNORMALITIES IN AN ACUTE EXACERBATION OF MYELOID LEUKAEMIA. Lancet. 1965 Mar 13;1(7385):609–610. doi: 10.1016/s0140-6736(65)91202-x. [DOI] [PubMed] [Google Scholar]
  26. Ratcliffe S. G., Stewart A. L., Melville M. M., Jacobs P. A., Keay A. J. Chromosome studies on 3500 newborn male infants. Lancet. 1970 Jan 17;1(7638):121–122. doi: 10.1016/s0140-6736(70)90469-1. [DOI] [PubMed] [Google Scholar]
  27. Ridler M. A., Pendrey M. J., Faunch J. A., Berg J. M. Association of D-D translocation with mongolism. J Ment Defic Res. 1969 Jun;13(2):89–98. doi: 10.1111/j.1365-2788.1969.tb01069.x. [DOI] [PubMed] [Google Scholar]
  28. Smith G. S., Tips R. L., Howard H. Autosomal mosaicism occurring in conjunction with Down's syndrome. Am J Ment Defic. 1965 Sep;70(2):218–222. [PubMed] [Google Scholar]
  29. Townes P. L. Latent aneuploidy in father and grandfather of doubly aneuploid child: mongolism in a child with 48 chromosomes. J Pediatr. 1968 Jul;73(1):97–100. doi: 10.1016/s0022-3476(68)80044-7. [DOI] [PubMed] [Google Scholar]
  30. Uchida I. A., Ray M., Ducan B. P. 21 trisomy with an XYY sex chromosome complement. J Pediatr. 1966 Aug;69(2):295–298. doi: 10.1016/s0022-3476(66)80338-4. [DOI] [PubMed] [Google Scholar]
  31. Welch J. P., Borgaonkar D. S., Herr H. M. Psychopathy, mental deficiency, aggressiveness and the XYY syndrome. Nature. 1967 Apr 29;214(5087):500–501. doi: 10.1038/214500a0. [DOI] [PubMed] [Google Scholar]
  32. ZERGOLLERN L., HOEFNAGEL D., BENIRSCHKE K., CORCORAN P. A. A PATIENT WITH TRISOMY 21 AND A RECIPROCAL TRANSLOCATION IN THE 13-15 GROUP. Cytogenetics. 1964;3:148–158. doi: 10.1159/000129806. [DOI] [PubMed] [Google Scholar]
  33. Zellweger H., Abbo G. Double trisomy and double trisomic mosaicism. Am J Dis Child. 1967 Mar;113(3):329–337. doi: 10.1001/archpedi.1967.02090180089007. [DOI] [PubMed] [Google Scholar]

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