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. 2004 Jan;166(1):631–635. doi: 10.1534/genetics.166.1.631

One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors.

Erik D Andrulis 1, David C Zappulla 1, Krassimira Alexieva-Botcheva 1, Carlos Evangelista 1, Rolf Sternglanz 1
PMCID: PMC1470702  PMID: 15020450

Abstract

In Saccharomyces cerevisiae, genes located at the telomeres and the HM loci are subject to transcriptional silencing. Here, we report results of screening a Gal4 DNA-binding domain hybrid library for proteins that cause silencing when targeted to a silencer-defective HMR locus.

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Selected References

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