Abstract
The integrated X chromosome database (IXDB) is a repository for physical mapping data of the human X chromosome. Its current content is the result of a strict integration of data stemming from many different sources. The main features of IXDB include a flexible and extendible schema, a comfortable and fully cross-referenced WWW interface (http://ixdb.mpimg-berlin-dahlem.mpg.de ) and a graphical map viewer implemented in JAVA. The database stores objects used in physical mapping as well as the maps resulting from this work, but a strong emphasis is placed on recording experiments that connect objects together. This should greatly contribute to fulfilling one of the major goals of the database: to support the construction of an integrated physical, genetic, transcript and sequence map of the human X chromosome.
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Selected References
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- Dib C., Fauré S., Fizames C., Samson D., Drouot N., Vignal A., Millasseau P., Marc S., Hazan J., Seboun E. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature. 1996 Mar 14;380(6570):152–154. doi: 10.1038/380152a0. [DOI] [PubMed] [Google Scholar]
- Nagaraja R., MacMillan S., Kere J., Jones C., Griffin S., Schmatz M., Terrell J., Shomaker M., Jermak C., Hott C. X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content. Genome Res. 1997 Mar;7(3):210–222. doi: 10.1101/gr.7.3.210. [DOI] [PubMed] [Google Scholar]
- Roest Crollius H., Ross M. T., Grigoriev A., Knights C. J., Holloway E., Misfud J., Li K., Playford M., Gregory S. G., Humphray S. J. An integrated YAC map of the human X chromosome. Genome Res. 1996 Oct;6(10):943–955. doi: 10.1101/gr.6.10.943. [DOI] [PubMed] [Google Scholar]
- Schuler G. D., Boguski M. S., Stewart E. A., Stein L. D., Gyapay G., Rice K., White R. E., Rodriguez-Tomé P., Aggarwal A., Bajorek E. A gene map of the human genome. Science. 1996 Oct 25;274(5287):540–546. [PubMed] [Google Scholar]
- Sixth International Workshop on Human X Chromosome Mapping 1995. Banff, Alberta, Canada, June 16-18, 1995. Report and abstracts. Cytogenet Cell Genet. 1995;71(4):307–342. doi: 10.1159/000134135. [DOI] [PubMed] [Google Scholar]
- Willard H. F., Cremers F., Mandel J. L., Monaco A. P., Nelson D. L., Schlessinger D. Report and abstracts of the Fifth International Workshop on Human X Chromosome Mapping 1994. Heidelberg, Germany, April 24-27, 1994. Cytogenet Cell Genet. 1994;67(4):295–358. doi: 10.1159/000133870. [DOI] [PubMed] [Google Scholar]