Abstract
A method of determining particle size distributions in lipid vesicle preparations is outlined. A vesicle suspension is modeled as a polydisperse mixture of spherical shells. The distribution of particle sizes in this mixture is approximated by a continuous, piecewise linear function called a first-order spline. Excellent simultaneous fits to photon correlation spectroscopy data gathered at several different angles are presented. An error analysis is included to indicate the resolution of the method.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Carlson F. D. The application of intensity fluctuation spectroscopy to molecular biology. Annu Rev Biophys Bioeng. 1975;4(00):243–264. doi: 10.1146/annurev.bb.04.060175.001331. [DOI] [PubMed] [Google Scholar]
- Huang C., Lee L. Diffusion studies on phosphatidylcholine vesicles. J Am Chem Soc. 1973 Jan 10;95(1):234–239. doi: 10.1021/ja00782a042. [DOI] [PubMed] [Google Scholar]
- Stock G. B. Application of splines to the calculation of bacterial swimming speed distributions. Biophys J. 1976 May;16(5):535–540. doi: 10.1016/S0006-3495(76)85708-6. [DOI] [PMC free article] [PubMed] [Google Scholar]