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. 1978 Feb;21(2):127–136. doi: 10.1016/S0006-3495(78)85513-1

The relationship between the transverse and longitudinal nuclear magnetic resonance relaxation rates of muscle water.

M M Civan, A M Achlama, M Shporer
PMCID: PMC1473356  PMID: 304746

Abstract

Whole frog sartorius and gastrocnemius muscles were incubated in Ringer's solutions, either unenriched or enriched with H2 17Oor 2D2O. Subsequently, the rates of transverse (1/T2) and of longitudinal (1/T1) nuclear magnetic relaxation were measured for 17O, 2D, and 1H at room temperature and at 8.1 MHz. The ratio (T1/T2) for 17O was measured to be approximately 1.5-2.0, close to the value roughly estimated from the Larmor frequency dependence of 1/T1 alone over the range 4.3-8.1 MHz. On the other hand (T1/T2) for 2D and 1H were both measured to lie in the range 9-11. Insofar as the entire 17O signal was detected, the data indicate the presence of an exchange mechanism between the major fraction of intracellular water and a minor fraction characterized by enhanced rates of relaxation. Possible molecular mechanisms are presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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