Abstract
Recent experiments (1,2) have shown that hydrophobic ions adsorbed to lipid membranes repel each other significantly at densities as low as one charge every few tens of square nanometers. This paper shows how to calculate the mutual repulsion of a population of such ions, assumed to be discrete but free to diffuse laterally in the plane of the membrane. The results fall between those for uniformly smeared charges (the "three-capacitor" model) and those for discrete charges immobilized on a periodic lattice.
Full text
PDF






Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Andersen O. S., Feldberg S., Nakadomari H., Levy S., McLaughlin S. Electrostatic interactions among hydrophobic ions in lipid bilayer membranes. Biophys J. 1978 Jan;21(1):35–70. doi: 10.1016/S0006-3495(78)85507-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bradshaw R. W., Robertson C. R. Effect of ionic polarizability on electrodiffusion in lipid bilayer membranes. J Membr Biol. 1975 Dec 4;25(1-2):93–114. doi: 10.1007/BF01868570. [DOI] [PubMed] [Google Scholar]
- Cole K. S. Zeta potential and discrete vs. uniform surface charges. Biophys J. 1969 Mar;9(3):465–469. doi: 10.1016/S0006-3495(69)86397-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Feldberg S. W., Delgado A. B. Inner voltage clamping. A method for studying interactions among hydrophobic ions in a lipid bilayer. Biophys J. 1978 Jan;21(1):71–86. doi: 10.1016/S0006-3495(78)85508-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nelson A. P., McQuarrie D. A. The effect of discrete charges on the electrical properties of a membrane. I. J Theor Biol. 1975 Nov;55(1):13–27. doi: 10.1016/s0022-5193(75)80106-8. [DOI] [PubMed] [Google Scholar]
