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. 1978 Jun;22(3):501–506. doi: 10.1016/S0006-3495(78)85502-7

Caffeine contracture and iodoacetate rigor in frog skeletal muscle. A comparison.

R P Schwarz Jr, R Hsieh, W H Johnson
PMCID: PMC1473479  PMID: 667298

Abstract

Frog sartorius muscle treated with 5.0 mM or greater caffeine exhibits stiffness similar to that obtained from muscle in iodoacetate rigor. The data provide quantitative evidence that suggests that caffeine at irreversible contracture-producing concentrations somehow induces a rigor or rigorlike state in skeletal muscle.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AXELSSON J., THESLEFF S. Activation of the contractile mechanism in striated muscle. Acta Physiol Scand. 1958 Oct 28;44(1):55–66. doi: 10.1111/j.1748-1716.1958.tb01608.x. [DOI] [PubMed] [Google Scholar]
  2. Borys H. K., Karler R. Effects of caffeine on the intracellular distribution of calcium in frog sartorius muscle. J Cell Physiol. 1971 Dec;78(3):387–404. doi: 10.1002/jcp.1040780308. [DOI] [PubMed] [Google Scholar]
  3. Burt C. T., Glonek T., Bárány M. Analysis of living tissue by phosphorus-31 magnetic resonance. Science. 1977 Jan 14;195(4274):145–149. doi: 10.1126/science.188132. [DOI] [PubMed] [Google Scholar]
  4. Caputo C. Caffeine- and potassium-induced contractures of frog striated muscle fibers in hypertonic solutions. J Gen Physiol. 1966 Sep;50(1):129–139. doi: 10.1085/jgp.50.1.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gebert G. Caffeine contracture of frog skeletal muscle and of single muscle fibers. Am J Physiol. 1968 Aug;215(2):296–298. doi: 10.1152/ajplegacy.1968.215.2.296. [DOI] [PubMed] [Google Scholar]
  6. Halpern W., Moss R. L. Elastic modulus and stress relationships in stretched and shortened frog sartorii. Am J Physiol. 1976 Jan;230(1):205–210. doi: 10.1152/ajplegacy.1976.230.1.205. [DOI] [PubMed] [Google Scholar]
  7. Lehninger A. L. Mitochondria and calcium ion transport. Biochem J. 1970 Sep;119(2):129–138. doi: 10.1042/bj1190129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Murphy R. A. Correlations of ATP content with mechanical properties of metabolically inhibited muscle. Am J Physiol. 1966 Nov;211(5):1082–1088. doi: 10.1152/ajplegacy.1966.211.5.1082. [DOI] [PubMed] [Google Scholar]
  9. RITCHIE J. M. The effect of nitrate on the active state of muscle. J Physiol. 1954 Oct 28;126(1):155–168. doi: 10.1113/jphysiol.1954.sp005200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Sakai T., Geffner E. S., Sandow A. Caffeine contracture in muscle with disrupted transverse tubules. Am J Physiol. 1971 Mar;220(3):712–717. doi: 10.1152/ajplegacy.1971.220.3.712. [DOI] [PubMed] [Google Scholar]
  11. Weber A., Herz R. The relationship between caffeine contracture of intact muscle and the effect of caffeine on reticulum. J Gen Physiol. 1968 Nov;52(5):750–759. doi: 10.1085/jgp.52.5.750. [DOI] [PMC free article] [PubMed] [Google Scholar]

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