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. 1978 Sep;23(3):407–425. doi: 10.1016/S0006-3495(78)85459-9

Structure determination of lipid bilayers.

C R Worthington, R S Kharf
PMCID: PMC1473535  PMID: 698345

Abstract

A method of determining the phases of X-ray reflections from oriented model membrane systems at low resolution is described. The method involves deconvolution and requires that d less than or equal to 2v where v is the width of the head group region within the bilayer and d is the thickness of the bilayer. The method can be used with a single set of X-ray data and applies to lipid bilayers which have a relatively constant density in the hydrocarbon region. Phases for the first five or six orders of phosphatidylethanolamine and lecithin are derived. A refined analysis based upon deconvolution but using information inherent in the Fourier profile is also described.

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Selected References

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