Abstract
This report is based on an analysis of deaths in 4519 battery plant workers and 2300 lead production or smelter workers during the years 1947 to 1980. Causes were coded to the seventh (1955) revision of the International Classification of Diseases. There were significant excess deaths for "other hypertensive disease" (444-447) and "chronic nephritis" (592-594) in both cohorts, the standardized mortality ratios (SMRs) being 320 and 475, respectively, for the former causes and 222 and 265 for the latter. Proportionate mortality analysis, which adjusted for race, also showed elevated ratios, 241 and 388 for the former causes and 296 and 186 for the latter. Deaths from other hypertension-related diseases did not show comparable excesses. Renal cancer deaths were fewer than expected, SMRs being 41 and 74, respectively.
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- Baker E. L., Jr, Goyer R. A., Fowler B. A., Khettry U., Bernard D. B., Adler S., White R. D., Babayan R., Feldman R. G. Occupational lead exposure, nephropathy, and renal cancer. Am J Ind Med. 1980;1(2):139–148. doi: 10.1002/ajim.4700010204. [DOI] [PubMed] [Google Scholar]
- Batuman V., Landy E., Maesaka J. K., Wedeen R. P. Contribution of lead to hypertension with renal impairment. N Engl J Med. 1983 Jul 7;309(1):17–21. doi: 10.1056/NEJM198307073090104. [DOI] [PubMed] [Google Scholar]
- Emmerson B. T. Chronic lead nephropathy. Kidney Int. 1973 Jul;4(1):1–5. doi: 10.1038/ki.1973.73. [DOI] [PubMed] [Google Scholar]
- Goyer R. A., Rhyne B. C. Pathological effects of lead. Int Rev Exp Pathol. 1973;12:1–77. [PubMed] [Google Scholar]
- Lilis R., Fischbein A., Valciukas J. A., Blumberg W., Selikoff I. J. Kidney function and lead: relationships in several occupational groups with different levels of exposure. Am J Ind Med. 1980;1(3-4):405–412. doi: 10.1002/ajim.4700010318. [DOI] [PubMed] [Google Scholar]
- Lilis R. Long-term occupational lead exposure, chronic nephropathy, and renal cancer: a case report. Am J Ind Med. 1981;2(3):293–297. doi: 10.1002/ajim.4700020309. [DOI] [PubMed] [Google Scholar]
- Morgan J. M., Hartley M. W., Miller R. E. Nephropathy in chronic lead poisoning. Arch Intern Med. 1966 Jul;118(1):17–29. [PubMed] [Google Scholar]
- Pirkle J. L., Schwartz J., Landis J. R., Harlan W. R. The relationship between blood lead levels and blood pressure and its cardiovascular risk implications. Am J Epidemiol. 1985 Feb;121(2):246–258. doi: 10.1093/oxfordjournals.aje.a113995. [DOI] [PubMed] [Google Scholar]
- Selevan S. G., Landrigan P. J., Stern F. B., Jones J. H. Mortality of lead smelter workers. Am J Epidemiol. 1985 Oct;122(4):673–683. doi: 10.1093/oxfordjournals.aje.a114146. [DOI] [PubMed] [Google Scholar]
- Wedeen R. P., Maesaka J. K., Weiner B., Lipat G. A., Lyons M. M., Vitale L. F., Joselow M. M. Occupational lead nephropathy. Am J Med. 1975 Nov;59(5):630–641. doi: 10.1016/0002-9343(75)90224-7. [DOI] [PubMed] [Google Scholar]