Abstract
Studies performed earlier have shown a positive relation between blood lead (a parameter for lead body burden) and blood pressure, whereas such a relation between urine cadmium (a parameter for cadmium body burden) and blood pressure could not be shown. Median (i.e., 50th percentile, P50) blood levels in the general population in the Netherlands are in the range of 80 to 150 micrograms/L. Persons occupationally exposed to lead show median blood lead levels that may exceed 400 micrograms/L. To study causality, a prospective study among lead workers is desired.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Kirkby H., Gyntelberg F. Blood pressure and other cardiovascular risk factors of long-term exposure to lead. Scand J Work Environ Health. 1985 Feb;11(1):15–19. doi: 10.5271/sjweh.2259. [DOI] [PubMed] [Google Scholar]
- Kromhout D., Wibowo A. A., Herber R. F., Dalderup L. M., Heerdink H., de Lezenne Coulander C., Zielhuis R. L. Trace metals and coronary heart disease risk indicators in 152 elderly men (the Zutphen Study). Am J Epidemiol. 1985 Sep;122(3):378–385. doi: 10.1093/oxfordjournals.aje.a114118. [DOI] [PubMed] [Google Scholar]
- Pirkle J. L., Schwartz J., Landis J. R., Harlan W. R. The relationship between blood lead levels and blood pressure and its cardiovascular risk implications. Am J Epidemiol. 1985 Feb;121(2):246–258. doi: 10.1093/oxfordjournals.aje.a113995. [DOI] [PubMed] [Google Scholar]
- Zielhuis R. L., del Castilho P., Herber R. F., Wibowo A. A., Sallé H. J. Concentrations of lead and other metals in blood of two and three year-old children living near a secondary smelter. Int Arch Occup Environ Health. 1979 Jan 15;42(3-4):231–239. doi: 10.1007/BF00377777. [DOI] [PubMed] [Google Scholar]
- de Kort W. L., Verschoor M. A., Wibowo A. A., van Hemmen J. J. Occupational exposure to lead and blood pressure: a study in 105 workers. Am J Ind Med. 1987;11(2):145–156. doi: 10.1002/ajim.4700110204. [DOI] [PubMed] [Google Scholar]