Abstract
Bovine respiratory disease (BRD) remains a significant cost to both the beef and dairy industries. In the United States, an estimated 640 million dollars is lost annually due to BRD. Losses are largely a result of pneumonic pasteurellosis ("shipping fever"), enzootic pneumonia of calves, and atypical interstitial pneumonia. In Canada, over 80% of the biologics licensed for use in cattle are against agents associated with BRD. The objectives of this paper were (a) to summarize information available concerning commercial vaccines currently used in Canada for protection against BRD, and (b) to provide an easily accessible resource for veterinary practitioners and researchers. Information from the most recent Compendium of Veterinary Products has been tabulated for each vaccine by trade name, according to vaccine type, and the pathogens against which they are designed to protect. Additional information from published articles (peer-reviewed and other) has been provided and referenced.
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- Ames T. R. Dairy calf pneumonia. The disease and its impact. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):379–391. doi: 10.1016/S0749-0720(15)30303-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Baker J. C., Ellis J. A., Clark E. G. Bovine respiratory syncytial virus. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):425–454. doi: 10.1016/s0749-0720(15)30307-8. [DOI] [PubMed] [Google Scholar]
- Belknap E. B., Baker J. C., Patterson J. S., Walker R. D., Haines D. M., Clark E. G. The role of passive immunity in bovine respiratory syncytial virus-infected calves. J Infect Dis. 1991 Mar;163(3):470–476. doi: 10.1093/infdis/163.3.470. [DOI] [PubMed] [Google Scholar]
- Brar J. S., Johnson D. W., Muscoplat C. C., Shope R. E., Jr, Meiske J. C. Maternal immunity to infectious bovine rhinotracheitis and bovine viral diarrhea viruses: duration and effect on vaccination in young calves. Am J Vet Res. 1978 Feb;39(2):241–244. [PubMed] [Google Scholar]
- Brownlie J. The pathogenesis of bovine virus diarrhoea virus infections. Rev Sci Tech. 1990 Mar;9(1):43–59. doi: 10.20506/rst.9.1.491. [DOI] [PubMed] [Google Scholar]
- Burroughs A. L., Morrill J. L., Bostwick J. L., Ridley R. K., Fryer H. C. Immune responses of dairy cattle to parainfluenza-3 virus in intranasal infectious bovine rhinotracheitis-parainfluenza-3 virus vaccines. Can J Comp Med. 1982 Jul;46(3):264–266. [PMC free article] [PubMed] [Google Scholar]
- Confer A. W. Immunogens of Pasteurella. Vet Microbiol. 1993 Nov;37(3-4):353–368. doi: 10.1016/0378-1135(93)90034-5. [DOI] [PubMed] [Google Scholar]
- Confer A. W., Panciera R. J., Mosier D. A. Bovine pneumonic pasteurellosis: immunity to Pasteurella haemolytica. J Am Vet Med Assoc. 1988 Nov 15;193(10):1308–1316. [PubMed] [Google Scholar]
- Conlon J. A., Gallo G. F., Shewen P. E., Adlam C. Comparison of protection of experimentally challenged cattle vaccinated once or twice with a Pasteurella haemolytica bacterial extract vaccine. Can J Vet Res. 1995 Jul;59(3):179–182. [PMC free article] [PubMed] [Google Scholar]
- Corbeil L. B., Gogolewski R. P. Mechanisms of bacterial injury. Vet Clin North Am Food Anim Pract. 1985 Jul;1(2):367–376. doi: 10.1016/s0749-0720(15)31331-1. [DOI] [PubMed] [Google Scholar]
- Ellis J. A., Hassard L. E., Cortese V. S., Morley P. S. Effects of perinatal vaccination on humoral and cellular immune responses in cows and young calves. J Am Vet Med Assoc. 1996 Feb 1;208(3):393–400. [PubMed] [Google Scholar]
- Ellis J. A., Hassard L. E., Morley P. S. Bovine respiratory syncytial virus-specific immune responses in calves after inoculation with commercially available vaccines. J Am Vet Med Assoc. 1995 Feb 1;206(3):354–361. [PubMed] [Google Scholar]
- Engelken T. J. Preventative programs for respiratory disease in cow/calf operations. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):647–660. doi: 10.1016/s0749-0720(15)30316-9. [DOI] [PubMed] [Google Scholar]
- Griffin D. Economic impact associated with respiratory disease in beef cattle. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):367–377. doi: 10.1016/s0749-0720(15)30302-9. [DOI] [PubMed] [Google Scholar]
- Harland R. J., Potter A. A., van Drunen-Littel-van den Hurk S., Van Donkersgoed J., Parker M. D., Zamb T. J., Janzen E. D. The effect of subunit or modified live bovine herpesvirus-1 vaccines on the efficacy of a recombinant Pasteurella haemolytica vaccine for the prevention of respiratory disease in feedlot calves. Can Vet J. 1992 Nov;33(11):734–741. [PMC free article] [PubMed] [Google Scholar]
- Johnson E. G. Feedlot management practices and bovine respiratory disease. Vet Clin North Am Food Anim Pract. 1985 Jul;1(2):413–418. doi: 10.1016/s0749-0720(15)31334-7. [DOI] [PubMed] [Google Scholar]
- Jones C. D. Mucociliary clearance from the calf lung. Can J Comp Med. 1983 Jul;47(3):265–269. [PMC free article] [PubMed] [Google Scholar]
- Kahrs R. F. Rational basis for an immunization program against the common diseases of the bovine respiratory tract. Can Vet J. 1974 Sep;15(9):252–256. [PMC free article] [PubMed] [Google Scholar]
- Kapil S., Basaraba R. J. Infectious bovine rhinotracheitis, parainfluenza-3, and respiratory coronavirus. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):455–469. doi: 10.1016/S0749-0720(15)30308-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knight A. P., Pierson R. E., Hoerlein A. B., Collier J. H., Horton D. P., Pruett J. B. Effect of vaccination time on morbidity, mortality, and weight gains of feeder calves. J Am Vet Med Assoc. 1972 Jul;161(1):45–48. [PubMed] [Google Scholar]
- Levings R. L., Henderson L. M., Metz C. A. In vitro potency assays for nonreplicating veterinary vaccines: comparison to in vivo assays and considerations in assay development. Vet Microbiol. 1993 Nov;37(3-4):201–219. doi: 10.1016/0378-1135(93)90023-z. [DOI] [PubMed] [Google Scholar]
- Liggitt H. D. Defense mechanisms in the bovine lung. Vet Clin North Am Food Anim Pract. 1985 Jul;1(2):347–366. doi: 10.1016/s0749-0720(15)31330-x. [DOI] [PubMed] [Google Scholar]
- Lillie L. E. The bovine respiratory disease complex. Can Vet J. 1974 Sep;15(9):233–242. [PMC free article] [PubMed] [Google Scholar]
- Martin S. W. Vaccination: Is it Effective in Preventing Respiratory Disease or Influencing Weight Gains in Feedlot Calves? Can Vet J. 1983 Jan;24(1):10–19. [PMC free article] [PubMed] [Google Scholar]
- Mechor G. D., Rousseaux C. G., Radostits O. M., Babiuk L. A., Petrie L. Protection of newborn calves against fatal multisystemic infectious bovine rhinotracheitis by feeding colostrum from vaccinated cows. Can J Vet Res. 1987 Oct;51(4):452–459. [PMC free article] [PubMed] [Google Scholar]
- Menanteau-Horta A. M., Ames T. R., Johnson D. W., Meiske J. C. Effect of maternal antibody upon vaccination with infectious bovine rhinotracheitis and bovine virus diarrhea vaccines. Can J Comp Med. 1985 Jan;49(1):10–14. [PMC free article] [PubMed] [Google Scholar]
- Miller J. M., Van der Maaten M. J., Whetstone C. A. Infertility in heifers inoculated with modified-live bovine herpesvirus-1 vaccinal strains against infectious bovine rhinotracheitis on postbreeding day 14. Am J Vet Res. 1989 Apr;50(4):551–554. [PubMed] [Google Scholar]
- Mosier D. A. Bacterial pneumonia. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):483–493. doi: 10.1016/s0749-0720(15)30310-8. [DOI] [PubMed] [Google Scholar]
- Mosier D. A., Confer A. W., Panciera R. J. The evolution of vaccines for bovine pneumonic pasteurellosis. Res Vet Sci. 1989 Jul;47(1):1–10. [PubMed] [Google Scholar]
- Perino L. J., Rupp G. P. Immunization of the beef cow and its influence on fetal and neonatal calf health. Vet Clin North Am Food Anim Pract. 1994 Mar;10(1):15–34. doi: 10.1016/s0749-0720(15)30587-9. [DOI] [PubMed] [Google Scholar]
- Phillip J. I. Bovine respiratory disease: is control possible? Vet Rec. 1972 May 13;90(20):552–555. doi: 10.1136/vr.90.20.552. [DOI] [PubMed] [Google Scholar]
- Potgieter L. N. Bovine respiratory tract disease caused by bovine viral diarrhea virus. Vet Clin North Am Food Anim Pract. 1997 Nov;13(3):471–481. doi: 10.1016/s0749-0720(15)30309-1. [DOI] [PubMed] [Google Scholar]
- Ribble C. S., Jim G. K., Janzen E. D. Efficacy of immunization of feedlot calves with a commercial Haemophilus somnus bacterin. Can J Vet Res. 1988 Apr;52(2):191–198. [PMC free article] [PubMed] [Google Scholar]
- Srinand S., Hsuan S. L., Yoo H. S., Maheswaran S. K., Ames T. R., Werdin R. E. Comparative evaluation of antibodies induced by commercial Pasteurella haemolytica vaccines using solid phase immunoassays. Vet Microbiol. 1996 Apr;49(3-4):181–195. doi: 10.1016/0378-1135(95)00187-5. [DOI] [PubMed] [Google Scholar]
- Storz J., Stine L., Liem A., Anderson G. A. Coronavirus isolation from nasal swab samples in cattle with signs of respiratory tract disease after shipping. J Am Vet Med Assoc. 1996 May 1;208(9):1452–1455. [PubMed] [Google Scholar]
- Tanner J. E., Morgan A. P. Design and analysis of veterinary vaccine efficacy trials. Vet Microbiol. 1993 Nov;37(3-4):221–230. doi: 10.1016/0378-1135(93)90024-2. [DOI] [PubMed] [Google Scholar]
- Todd J. D. Development of intranasal vaccination for the immunization of cattle against infectious bovine rhinotracheitis. Can Vet J. 1974 Sep;15(9):257–259. [PMC free article] [PubMed] [Google Scholar]
- Van Donkersgoed J., Schumann F. J., Harland R. J., Potter A. A., Janzen E. D. The effect of route and dosage of immunization on the serological response to a Pasteurella haemolytica and Haemophilus somnus vaccine in feedlot calves. Can Vet J. 1993 Dec;34(12):731–735. [PMC free article] [PubMed] [Google Scholar]
- Wieringa F. L., Curtis R. A., Willoughby R. A. The influence of preconditioning on plasma corticosteroid levels, rectal temperatures and the incidence of shipping fever in beef calves. Can Vet J. 1976 Nov;17(11):280–286. [PMC free article] [PubMed] [Google Scholar]
- Wilbur L. A. Statistical methods for analysis of in vitro antigen quantification data for veterinary biologic products. Vet Microbiol. 1993 Nov;37(3-4):231–240. doi: 10.1016/0378-1135(93)90025-3. [DOI] [PubMed] [Google Scholar]
- Wittum T. E., Perino L. J. Passive immune status at postpartum hour 24 and long-term health and performance of calves. Am J Vet Res. 1995 Sep;56(9):1149–1154. [PubMed] [Google Scholar]
- Wittum T. E., Woollen N. E., Perino L. J., Littledike E. T. Relationships among treatment for respiratory tract disease, pulmonary lesions evident at slaughter, and rate of weight gain in feedlot cattle. J Am Vet Med Assoc. 1996 Aug 15;209(4):814–818. [PubMed] [Google Scholar]
- Woods G. T., Mansfield M. E., Webb R. J. A three year comparison of acute respiratory disease, shrink and weight gain in preconditioned and non-preconditioned Illinois beef calves sold at the same auction and mixed in a feedlot. Can J Comp Med. 1973 Jul;37(3):249–255. [PMC free article] [PubMed] [Google Scholar]
- Yates W. D. A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle. Can J Comp Med. 1982 Jul;46(3):225–263. [PMC free article] [PubMed] [Google Scholar]