Abstract
An intact male, Great Dane puppy was evaluated for weakness, lethargy, reluctance to move, and inability to stand. Hypertrophic osteodystrophy was diagnosed based on clinical and radiographic findings. Clinical signs, radiographic lesions, gross pathology, histopathology, etiology, and treatment of the disease are discussed.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abeles V., Harrus S., Angles J. M., Shalev G., Aizenberg I., Peres Y., Aroch I. Hypertrophic osteodystrophy in six weimaraner puppies associated with systemic signs. Vet Rec. 1999 Jul 31;145(5):130–134. doi: 10.1136/vr.145.5.130. [DOI] [PubMed] [Google Scholar]
- Alexander J. W. Selected skeletal dysplasias: craniomandibular osteopathy, multiple cartilaginous exostoses, and hypertrophic osteodystrophy. Vet Clin North Am Small Anim Pract. 1983 Feb;13(1):55–70. doi: 10.1016/s0195-5616(83)50004-1. [DOI] [PubMed] [Google Scholar]
- Grøndalen J. Metaphyseal osteopathy (hypertrophic osteodystrophy) in growing dogs. A clinical study. J Small Anim Pract. 1976 Nov;17(11):721–735. [PubMed] [Google Scholar]
- Hedhammar A., Krook L., Whalen J. P., Ryan G. D. Overnutrition and skeletal disease. An experimental study in growing Great Dane dogs. IV. Clinical observations. Cornell Vet. 1974 Apr;64(2 Suppl):32–45. [PubMed] [Google Scholar]
- Mee A. P., Gordon M. T., May C., Bennett D., Anderson D. C., Sharpe P. T. Canine distemper virus transcripts detected in the bone cells of dogs with metaphyseal osteopathy. Bone. 1993;14(1):59–67. doi: 10.1016/8756-3282(93)90257-b. [DOI] [PubMed] [Google Scholar]
- Schulz K. S., Payne J. T., Aronson E. Escherichia coli bacteremia associated with hypertrophic osteodystrophy in a dog. J Am Vet Med Assoc. 1991 Nov 1;199(9):1170–1173. [PubMed] [Google Scholar]
- Woodard J. C. Canine hypertrophic osteodystrophy, a study of the spontaneous disease in littermates. Vet Pathol. 1982 Jul;19(4):337–354. doi: 10.1177/030098588201900401. [DOI] [PubMed] [Google Scholar]