Abstract
Local tetanus was induced in rabbits by the intramuscular injection of tetanus toxin. The relative potency of drugs which abolished the muscle spasm was determined using quantitative electromyography and the accuracy of the method tested with mephenesin and thiopentone. It is suggested that the method is suitable for screening new drugs for clinical use.
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Selected References
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- WRIGHT E. A., MORGAN R. S., WRIGHT G. P. The site of action of the toxin in local tetanus. Lancet. 1952 Aug 16;2(6729):316–319. doi: 10.1016/s0140-6736(52)92478-1. [DOI] [PubMed] [Google Scholar]