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British Journal of Pharmacology and Chemotherapy logoLink to British Journal of Pharmacology and Chemotherapy
. 1959 Jun;14(2):158–163. doi: 10.1111/j.1476-5381.1959.tb01376.x

Assay of suxamethonium and laudexium on the frog rectus abdominis

R T Brittain, B G Chesher, H O J Collier, J J Grimshaw
PMCID: PMC1481804  PMID: 13662566

Abstract

Suxamethonium, like acetylcholine, causes contracture of the isolated rectus abdominis muscle of the frog, whereas laudexium antagonizes this effect. These actions may be used to assay both drugs with reasonable speed and fiducial limits, provided that changes in responsiveness of the preparation during the course of assay are met by suitable design and analysis. Small quantities of suxamethonium and laudexium may be assayed in certain body fluids.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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