Abstract
Iproniazid was found to inhibit formalin-induced oedema of the foot, dextran-induced oedema and cotton-pellet-induced granulomatous tissue in the rat. The presence of the adrenals was essential for the antiphlogistic activity. The antiphlogistic action was not accompanied by any antipyretic effect. Inhibition of formalin-induced oedema was also observed with phenylbutazone and with salicylamide.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARRITT A. S., SCHEID C. J., WIESEL L. L. Investigation of the synergism of isonicotinic acid hydrazide and cortisone. II. Long-term study of the synergistic action of isonicotinic acid hydrazide and cortisone acetate in the treatment of rheumatoid arthritis. Am J Med Sci. 1956 Oct;232(4):415–418. doi: 10.1097/00000441-195610000-00007. [DOI] [PubMed] [Google Scholar]
- GEORGES G., HEROLD M. Influence de la sérotonine sur l'oedéme plantaire au dextran chez le rat. C R Seances Soc Biol Fil. 1957;151(4):695–698. [PubMed] [Google Scholar]
- GEORGES G. Influence de la 5-hydroxy-tryptamine sur la réactivité du couple-hypophyso-surrénalien chez le rat. C R Seances Soc Biol Fil. 1957;151(4):692–695. [PubMed] [Google Scholar]
- MEIER R., SCHULER W., DESAULLES P. Zur Frage des Mechanismus der Hemmung des Bindegewebswachstums durch Cortisone. Experientia. 1950 Dec 15;6(12):469–471. doi: 10.1007/BF02154110. [DOI] [PubMed] [Google Scholar]
- SCHERBEL A. L. The effect of marsilid in patients having rheumatoid arthritis; the theoretical causal role of certain amine oxidases. J Clin Exp Psychopathol. 1958 Apr-Jun;19(2 Suppl 1):118–122. [PubMed] [Google Scholar]
- SETNIKAR I., MURMANN W. Osservazioni farmacologiche sull'estere solforico del paraossipropiofenone. Farmaco Sci. 1958;13(8):541–560. [PubMed] [Google Scholar]
- WIESEL L. L. Investigation of the synergism of isonicotinic acid hydrazide and cortisone. I. Effect of isonicotinic acid on the metabolism of cortisone by liver tissue. Am J Med Sci. 1956 Oct;232(4):412–414. doi: 10.1097/00000441-195610000-00006. [DOI] [PubMed] [Google Scholar]