Abstract
An aqueous extract of gluten, and its ultrafiltrate, depressed the peristaltic reflex of the rat jejunum. This effect was shared by similar extracts of mammalian skeletal muscle but not by such proteins as casein, gelatin, and albumin. Peptic-tryptic digestion did not abolish the effect, whereas acid hydrolysis of the active fractions destroyed the depressant substance.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ANDERSON C. M., ASTLEY R., FRENCH J. M., GERRARD J. W. The small intestine pattern in coeliac disease. Br J Radiol. 1952 Oct;25(298):526–530. doi: 10.1259/0007-1285-25-298-526. [DOI] [PubMed] [Google Scholar]
- ANDERSON C. M., FRAZER A. C., FRENCH J. M., HAWKINS C. F., ROSS C. A., SAMMONS H. G. The influence of gluten and antibacterial agents on fat absorption in the sprue syndrome. Gastroenterologia. 1954 Feb;81(2):98–103. doi: 10.1159/000199985. [DOI] [PubMed] [Google Scholar]
- ANDERSON C. M., FRENCH J. M., SAMMONS H. G., FRAZER A. C., GERRARD J. W., SMELLIE J. M. Coeliac disease; gastrointestinal studies and the effect of dietary wheat flour. Lancet. 1952 Apr 26;1(6713):836–842. doi: 10.1016/s0140-6736(52)90795-2. [DOI] [PubMed] [Google Scholar]
- FRAZER A. C., FLETCHER R. F., ROSS C. A., SHAW B., SAMMONS H. G., SCHNEIDER R. Gluten-induced enteropathy: the effect of partially digested gluten. Lancet. 1959 Sep 5;2(7097):252–255. doi: 10.1016/s0140-6736(59)92051-3. [DOI] [PubMed] [Google Scholar]
- ROSS C. A., FRAZER A. C., FRENCH J. M., GERRARD J. W., SAMMONS H. G., SMELLIE J. M. Coeliac disease; the relative importance of wheat gluten. Lancet. 1955 May 28;268(6874):1087–1091. doi: 10.1016/s0140-6736(55)90588-2. [DOI] [PubMed] [Google Scholar]
- VAN DE KAMER J. H., WEIJERS H. A., DICKE W. K. Coeliac disease. IV. An investigation into the injurious constituents of wheat in connection with their action on patients with coeliac disease. Acta Paediatr. 1953 May;42(3):223–231. doi: 10.1111/j.1651-2227.1953.tb05586.x. [DOI] [PubMed] [Google Scholar]