Abstract
The LD50 in mice for nicotine, (—)-nornicotine and allylnornicotine given intraperitoneally was respectively 10 mg/kg, 18.8 mg/kg and 93.3 mg/kg. Whilst nicotine inhibited the renal response in rats to water, (—)-nornicotine and allylnornicotine were without effect. Nicotine antidiuresis was not antagonized by (—)-nornicotine or by allylnornicotine.
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Selected References
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