Abstract
Levallorphan antagonizes the antidiuretic effect of morphine. It is at least 25 times as potent as nalorphine in this respect. However, neither levallorphan nor adiphenine antagonized the antidiuretic action of nicotine.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BECKETT A. H., CASY A. F., HARPER N. J., PHILLIPS P. M. Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds. J Pharm Pharmacol. 1956 Nov;8(11):860–873. [PubMed] [Google Scholar]
- BISSET G. W., WALKER J. M. The effects of nicotine, hexamethonium and ethanol on the secretion of the antidiuretic and oxytocic hormones of the rat. Br J Pharmacol Chemother. 1957 Dec;12(4):461–467. doi: 10.1111/j.1476-5381.1957.tb00166.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burn J. H., Truelove L. H., Burn I. Antidiuretic Action of Nicotine. Br Med J. 1945 Mar 24;1(4394):403–406. doi: 10.1136/bmj.1.4394.403. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FROMHERZ K., PELLMONT B. Morphinantagonisten. Experientia. 1952 Oct 15;8(10):394–395. doi: 10.1007/BF02176207. [DOI] [PubMed] [Google Scholar]
- GIARMAN N. J., MATTIE L. R., STEPHENSON Studies on the antidiuretic action of morphine. Science. 1953 Feb 27;117(3035):225–226. doi: 10.1126/science.117.3035.225. [DOI] [PubMed] [Google Scholar]
- Pickford M. The inhibitory effect of acetylcholine on water diuresis in the dog, and its pituitary transmission. J Physiol. 1939 Feb 14;95(1):226–238. doi: 10.1113/jphysiol.1939.sp003721. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SCHNIEDEN H., BLACKMORE E. K. The effect of nalorphine on the antidiuretic action of morphine in rats and men. Br J Pharmacol Chemother. 1955 Mar;10(1):45–50. doi: 10.1111/j.1476-5381.1955.tb00058.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TRIPOD J. Some relationships between anti-nicotine activity and specific antagonisms. Br J Pharmacol Chemother. 1949 Dec;4(4):323–328. doi: 10.1111/j.1476-5381.1949.tb00557.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WINTER C. A., GAFFNEY C. E., FLATAKER L. The effect of N-allylnormorphine upon the antidiuretic action of morphine. J Pharmacol Exp Ther. 1954 Jul;111(3):360–364. [PubMed] [Google Scholar]