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. 1972 Oct;12(10):1266–1284. doi: 10.1016/S0006-3495(72)86161-7

Cell Communication in the Basal Cells of the Human Epidermis

J Siegenbeek Van Heukelom, D W Slaaf, J C Van Der Leun
PMCID: PMC1484233  PMID: 5074742

Abstract

Electrotonic spread can be measured in the basal cells of the human epidermis. The communication between neighboring cells is high, whereas no leak to the intercellular spaces could be detected. The specific resistance of the membranes between the cells is about 10 Ωcm2. This finding suggests that for those particles that are able to pass the cell membrane the intracellular path through the epidermis is at least as suitable as the path through the intercellular spaces.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Furshpan E. J., Potter D. D. Low-resistance junctions between cells in embryos and tissue culture. Curr Top Dev Biol. 1968;3:95–127. doi: 10.1016/s0070-2153(08)60352-x. [DOI] [PubMed] [Google Scholar]
  2. Halprin K. M., Ohkawara A. Glucose entry into the human epidermis. II. The penetration of glucose into the human epidermis in vitro. J Invest Dermatol. 1967 Dec;49(6):561–568. doi: 10.1038/jid.1967.181. [DOI] [PubMed] [Google Scholar]
  3. Ingemansson-Nordqvist B., Kiistala U., Rorsman H. Culture of adult human epidermal cells obtained from roofs of suction blisters. Acta Derm Venereol. 1967;47(4):237–240. [PubMed] [Google Scholar]
  4. Kiistala U. Suction blister device for separation of viable epidermis from dermis. J Invest Dermatol. 1968 Feb;50(2):129–137. doi: 10.1038/jid.1968.15. [DOI] [PubMed] [Google Scholar]
  5. LOEWENSTEIN W. R., KANNO Y. STUDIES ON AN EPITHELIAL (GLAND) CELL JUNCTION. I. MODIFICATIONS OF SURFACE MEMBRANE PERMEABILITY. J Cell Biol. 1964 Sep;22:565–586. doi: 10.1083/jcb.22.3.565. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Loewenstein W. R., Nakas M., Socolar S. J. Junctional membrane uncoupling. Permeability transformations at a cell membrane junction. J Gen Physiol. 1967 Aug;50(7):1865–1891. doi: 10.1085/jgp.50.7.1865. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Loewenstein W. R., Penn R. D. Intercellular communication and tissue growth. II. Tissue regeneration. J Cell Biol. 1967 May;33(2):235–242. doi: 10.1083/jcb.33.2.235. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. MALKINSON F. D., KIRSCHENBAUM M. B. PERCUTANEOUS ABSORPTION OF C14-LABELED TRIAMCINOLONE ACETONIDE. Arch Dermatol. 1963 Oct;88:427–439. doi: 10.1001/archderm.1963.01590220059007. [DOI] [PubMed] [Google Scholar]
  9. Penn R. D. Ionic communication between liver cells. J Cell Biol. 1966 Apr;29(1):171–174. doi: 10.1083/jcb.29.1.171. [DOI] [PMC free article] [PubMed] [Google Scholar]

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