Abstract
Conduction speed (θ) in single myelinated Rana pipiens sciatic nerve fibers has been precisely measured using intracellular recording and on-line digital computer techniques. The dependence of relative speed on external Na concentration at 15°C has been found to be ln(θ1/θ2) = 0.524 (±0.018) ln ([Na+]1/[Na+]2) + 0.003. Thus θ has very close to a square root dependence on [Na+]0 for these fibers. This experimental finding is not in complete agreement with a theoretical prediction based on a solution of the Hodgkin-Huxley (H.H.) equations. The effect of small temperature variations around 15°C on θ has also been measured for Rana fibers in Ringer's solution. θ has close to an exponential dependence on T and a Q10 of 2.95 has been estimated.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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