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CMAJ : Canadian Medical Association Journal logoLink to CMAJ : Canadian Medical Association Journal
. 1987 Jan 1;136(1):45–47.

Atherosclerosis of coronary artery bypass grafts and smoking.

G M FitzGibbon, A J Leach, H P Kafka
PMCID: PMC1491589  PMID: 3491666

Abstract

Follow-up angiography was performed at selected intervals on 340 men who had undergone coronary artery bypass surgery. There were 1160 grafts, but 112 were excluded from study because they occluded shortly after the operation. After 5 years 115 patients were smokers and 225 were nonsmokers. The mean number of grafts per patient was similar in the two groups. We classified each graft according to irregularities in graft outlines and graft patency and found disease-free grafts in 39% of the smokers and 52% of the nonsmokers; the proportion of diseased or occluded grafts was greater in the smokers than in the nonsmokers. Our results do not identify the effect of smoking cessation after bypass surgery, but they do suggest that men who continue to smoke are at significantly greater risk of atherosclerosis and occlusion than nonsmoking men.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Auerbach O., Carter H. W., Garfinkel L., Hammond E. C. Cigarette smoking and coronary artery disease. A macroscopic and microscopic study. Chest. 1976 Dec;70(6):697–705. doi: 10.1378/chest.70.6.697. [DOI] [PubMed] [Google Scholar]
  2. Brower R. W., Laird-Meeter K., Serruys P. W., Meester G. T., Hugenholtz P. G. Long term follow-up after coronary artery bypass graft surgery. Progression and regression of disease in native coronary circulation and bypass grafts. Br Heart J. 1983 Jul;50(1):42–47. doi: 10.1136/hrt.50.1.42. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Campeau L., Enjalbert M., Lespérance J., Bourassa M. G., Kwiterovich P., Jr, Wacholder S., Sniderman A. The relation of risk factors to the development of atherosclerosis in saphenous-vein bypass grafts and the progression of disease in the native circulation. A study 10 years after aortocoronary bypass surgery. N Engl J Med. 1984 Nov 22;311(21):1329–1332. doi: 10.1056/NEJM198411223112101. [DOI] [PubMed] [Google Scholar]
  4. Cashin W. L., Brooks S. H., Blankenhorn D. H., Selzer R. H., Sanmarco M. E., Benjauthrit B. Computerized edge tracking and lesion measurement in coronary angiograms. A pilot study comparing smokers with non-smokers. Atherosclerosis. 1984 Sep;52(3):295–300. doi: 10.1016/0021-9150(84)90059-5. [DOI] [PubMed] [Google Scholar]
  5. Castelli W. P., Garrison R. J., Dawber T. R., McNamara P. M., Feinleib M., Kannel W. B. The filter cigarette and coronary heart disease: the Framingham study. Lancet. 1981 Jul 18;2(8238):109–113. doi: 10.1016/s0140-6736(81)90297-x. [DOI] [PubMed] [Google Scholar]
  6. Castleden C. M., Cole P. V. Inhalation of tobacco smoke by pipe and cigar smokers. Lancet. 1973 Jul 7;2(7819):21–22. doi: 10.1016/s0140-6736(73)91950-8. [DOI] [PubMed] [Google Scholar]
  7. Fielding J. E. Smoking: health effects and control (1). N Engl J Med. 1985 Aug 22;313(8):491–498. doi: 10.1056/NEJM198508223130807. [DOI] [PubMed] [Google Scholar]
  8. FitzGibbon G. M., Leach A. J., Keon W. J., Burton J. R., Kafka H. P. Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, one year, and five years after operation. J Thorac Cardiovasc Surg. 1986 May;91(5):773–778. [PubMed] [Google Scholar]
  9. Goldman A. L. Carboxyhemoglobin levels in primary and secondary cigar and pipe smokers. Chest. 1977 Jul;72(1):33–35. doi: 10.1378/chest.72.1.33. [DOI] [PubMed] [Google Scholar]
  10. Gyntelberg F., Lauridsen L., Pedersen P. B., Schubell K. Smoking and risk of myocardial infarction in Copenhagen men aged 40-59 with special reference to cheroot smoking. Lancet. 1981 May 2;1(8227):987–989. doi: 10.1016/s0140-6736(81)91743-8. [DOI] [PubMed] [Google Scholar]
  11. Holbrook J. H., Grundy S. M., Hennekens C. H., Kannel W. B., Strong J. P. Cigarette smoking and cardiovascular diseases. A statement for health professionals by a task force appointed by the steering committee of the American Heart Association. Circulation. 1984 Dec;70(6):1114A–1117A. [PubMed] [Google Scholar]
  12. Klein L. W. Cigarette smoking, atherosclerosis and the coronary hemodynamic response: a unifying hypothesis. J Am Coll Cardiol. 1984 Nov;4(5):972–974. doi: 10.1016/s0735-1097(84)80059-5. [DOI] [PubMed] [Google Scholar]
  13. Lie J. T., Lawrie G. M., Morris G. C., Jr Aortocoronary bypass saphenous vein graft atherosclerosis. Anatomic study of 99 vein grafts from normal and hyperlipoproteinemic patients up to 75 months postoperatively. Am J Cardiol. 1977 Dec;40(6):906–914. doi: 10.1016/0002-9149(77)90041-8. [DOI] [PubMed] [Google Scholar]
  14. Ramsdale D. R., Faragher E. B., Bray C. L., Bennett D. H., Ward C., Beton D. C. Smoking and coronary artery disease assessed by routine coronary arteriography. Br Med J (Clin Res Ed) 1985 Jan 19;290(6463):197–200. doi: 10.1136/bmj.290.6463.197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Turner J. A., Sillett R. W., McNicol M. W. Effect of cigar smoking on carboxyhaemoglobin and plasma nicotine concentrations in primary pipe and cigar smokers and ex-cigarette smokers. Br Med J. 1977 Nov 26;2(6099):1387–1389. doi: 10.1136/bmj.2.6099.1387. [DOI] [PMC free article] [PubMed] [Google Scholar]

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